1592-48-9Relevant academic research and scientific papers
An improved synthesis of the anti-picornavirus flavone 3-O-methylquercetin
Boers, Frank,Deng, Bo-Liang,Lemiere, Guy,Lepoivre, Jozef,De Groot, Alex,Dommisse, Roger,Vlietinck, Arnold J.
, p. 313 - 316 (1997)
Two optimised procedures to synthesise 3-O-methylquercetin (1), an important antivirally active flavone, are presented: one is based on an Allan-Robinson condensation, the other one on a modified phase transfer catalysed Baker-Venkataraman transformation.
SYNTHESIS OF 5,8-DIHYDROXY-6,7-DIMETHOXYFLAVONES AND REVISED STRUCTURES FOR SOME NATURAL FLAVONES
Horie, Tokunaru,Kawamura, Yasuhiko,Yamamoto, Hitoshi,Kitou, Takeshi,Yamashita, Kazuyo
, p. 1201 - 1210 (2007/10/02)
Six 5,8-dihydroxy-6,7-dimethoxyflavones and three 8-hydroxy-5,6,7-trimethoxyflavones were synthesized from 2',5'-dihydroxy-3',4',6'-trimethoxyacetophenone by adapting the selective O-alkylation and dealkylation, and the differentiation between the flavones and their isomeric 6-hydroxyflavones was clarified by 1H NMR and UV spectra.Four natural flavones proposed as 5,8-dihydroxy-6,7-dimethoxyflavones, must have other structures and three are shown to be isomeric 5,7-dihydroxy-6,8-dimethoxyflavones.A flavone, isolated from Helichrysum, is revised to the isomeric 7-hydroxy-5,6,7-trimethoxyflavone,
