C₆₆H₆₈N₂O₁₀

Base Information

• Chemical Name: C₆₆H₆₈N₂O₁₀
• CAS No.: 1436431-43-4
• Molecular Formula: C₆₆H₆₈N₂O₁₀
• Molecular Weight: 1049.27
• Mol file: 1436431-43-4.mol

Synonyms:C₆₆H₆₈N₂O₁₀

Chemical Property of C₆₆H₆₈N₂O₁₀

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₆₆H₆₈N₂O₁₀

There total 3 articles about C₆₆H₆₈N₂O₁₀ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

(R,R)-N,N'-di(tert-butoxycarbonyl)-1,2-bis(p-hydroxyphenyl)-1,2-diaminoethane (896155-88-7) + 3,5-bis(benzyloxy)benzyl bromide (24131-32-6) → C66H68N2O10 (1436431-43-4)

Guidance literature:

With potassium carbonate; potassium iodide; In acetone; at 70 ℃; Reflux; Inert atmosphere; Schlenk technique;

DOI:10.1016/j.ica.2013.05.035

Reference yield:

(1R,2R)-1,2-bis(4-methoxyphenyl)ethane-1,2-diamine (58520-03-9,117106-36-2) → C66H68N2O10 (1436431-43-4)

Guidance literature:

Multi-step reaction with 3 steps

1.1: boron tribromide / dichloromethane / 24 h / -20 °C

2.1: sodium hydroxide / pH 7-8

2.2: 24 h

3.1: potassium carbonate; potassium iodide / acetone / 70 °C / Reflux; Inert atmosphere; Schlenk technique

With boron tribromide; potassium carbonate; potassium iodide; sodium hydroxide; In dichloromethane; acetone;

DOI:10.1016/j.ica.2013.05.035

Reference yield:

C14H16N2O2 → C66H68N2O10 (1436431-43-4)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hydroxide / pH 7-8

1.2: 24 h

2.1: potassium carbonate; potassium iodide / acetone / 70 °C / Reflux; Inert atmosphere; Schlenk technique

With potassium carbonate; potassium iodide; sodium hydroxide; In acetone;

DOI:10.1016/j.ica.2013.05.035

upstream raw materials:

(R,R)-N,N'-di(tert-butoxycarbonyl)-1,2-bis(p-hydroxyphenyl)-1,2-diaminoethane

3,5-bis(benzyloxy)benzyl bromide

(1R,2R)-1,2-bis(4-methoxyphenyl)ethane-1,2-diamine

Refernces