24131-32-6

Basic information

• Product Name: 3,5-BIS(BENZYLOXY)BENZYL BROMIDE
• Synonyms: 5-BROMOMETHYLRESORCINOL DIBENZYL ETHER;3,5-BIS(BENZYLOXY)BENZYL BROMIDE;3,5-DIBENZYLOXY-ALPHA-BROMOTOLUENE;3,5-DIBENZYLOXYBENZYL BROMIDE;3,5-DIBENZYLOXYBENZYL BROMIDE 98+%;Benzene,1-(bromomethyl)-3,5-bis(phenylmethoxy)-;3,5-Bis(benzyloxy)benzyl Bromide 3,5-Dibenzyloxy-alpha-bromotoluene;(((5-(bromomethyl)-1,3-phenylene)bis(oxy))bis(methylene))dibenzene
• CAS NO: 24131-32-6
• Molecular Formula: C₂₁H₁₉BrO₂
• Molecular Weight: 383.28
• Product Categories: Building Blocks for Dendrimers;Functional Materials
• Mol File: 24131-32-6.mol
• Article Data: 33

Chemical Properties

• Melting Point: 86-88
• Boiling Point: 504.3°C at 760 mmHg
• Flash Point: 209.8°C
• Appearance: /
• Density: 1.329±0.06 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 8.44E-10mmHg at 25°C
• Refractive Index: 1.619
• Storage Temp.: Refrigerator
• CAS DataBase Reference: 3,5-BIS(BENZYLOXY)BENZYL BROMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-BIS(BENZYLOXY)BENZYL BROMIDE(24131-32-6)
• EPA Substance Registry System: 3,5-BIS(BENZYLOXY)BENZYL BROMIDE(24131-32-6)

Safety Data

• Hazard Codes: Xi
• RIDADR: UN 1759 8/PG III
• HazardClass: IRRITANT
• PackingGroup: III
• Hazardous Substances Data: 24131-32-6(Hazardous Substances Data)

Usage

Description

3,5-BIS(BENZYLOXY)BENZYL BROMIDE, with the molecular formula C21H19BrO2, is an organic compound characterized by the presence of two benzyloxy groups and a bromide atom attached to a benzyl moiety. It is widely recognized for its role in organic synthesis, particularly in the formation of carbon-carbon and carbon-heteroatom bonds, and is instrumental in palladium-catalyzed cross-coupling reactions and other chemical transformations.

Uses

Used in Organic Synthesis:
3,5-BIS(BENZYLOXY)BENZYL BROMIDE is used as a reagent for the formation of carbon-carbon and carbon-heteroatom bonds, which are crucial in constructing complex organic molecules and frameworks.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, 3,5-BIS(BENZYLOXY)BENZYL BROMIDE is used as a key building block for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Fine Chemicals Production:
3,5-BIS(BENZYLOXY)BENZYL BROMIDE is also utilized in the production of fine chemicals, where its unique structure and reactivity are harnessed to create specialty chemicals for various applications.
Used in Palladium-Catalyzed Cross-Coupling Reactions:
3,5-BIS(BENZYLOXY)BENZYL BROMIDE is employed as a reactant in palladium-catalyzed cross-coupling reactions, a significant method in modern organic chemistry for forming carbon-carbon bonds, which is essential for the synthesis of complex organic molecules and advanced materials.

InChI:InChI=1/C21H19BrO2/c22-14-19-11-20(23-15-17-7-3-1-4-8-17)13-21(12-19)24-16-18-9-5-2-6-10-18/h1-13H,14-16H2

Upstream product

• 24131-31-5 3,5-dibenzyloxybenzyl alcohol 
• 100-44-7 benzyl chloride 
• 100-39-0 benzyl bromide 
• 29654-55-5 5-(hydroxymethyl)benzene-1,3-diol 
• 28917-43-3 3,5-dibenzyloxybenzoic acid 
• 50513-72-9 (3,5-di-benzyloxy)benzoic acid benzyl ester 
• 99-10-5 3,5-Dihydroxybenzoic acid 
• 58605-10-0 methyl 3,5-bis(benzyloxy)benzoate 
• 2150-44-9 1-carbomethoxy-3,5-dihydroxybenzene 
• 80457-61-0 methanesulfonyl 3,5-dibenzyloxybenzyl alcohol 

Downstream Products

• 185413-77-8 1-(3,5-Bis-benzyloxy-phenyl)-2-methyl-heptane-3,5-dione 
• 58604-84-5 (3',5'-dibenzyloxy)phenylacetonitrile 
• 427901-25-5 {3-Benzyloxy-5-[3-benzyloxy-5-(3,5-bis-benzyloxy-benzyloxy)-benzyloxy]-phenyl}-methanol 
• 239447-26-8 4,4'-bis[3'',5''-bis(benzyloxy)phenylethyl]-2,2'-bipyridine 
• 255827-61-3 {4-[(2S,3R)-3-(3,5-Bis-benzyloxy-benzyloxy)-2-(3,5-bis-benzyloxy-benzyloxymethyl)-butyl]-benzyloxy}-tert-butyl-diphenyl-silane 
• 309758-39-2 4-allyloxy-3,5-bis-(3,5-bis-benzyloxy-benzyloxy)-benzoic acid methyl ester 
• 364069-24-9 3,4-bis-(3,5-bis-benzyloxy-benzyloxymethyl)-furan 
• 357219-28-4 9,9-bis[(3,5-bis(benzyloxy)benzyl)]-2,7-dibromofluorene 
• 691413-54-4 2,9-bis-{2-[4-(3,5-bis-benzyloxy-benzyloxy)-phenyl]-ethyl}-[1,10]phenanthroline 
• 466635-88-1 C₅₀H₄₂O₆ 
• 909389-78-2 (NC₅H₄CC)2C₆H₃OCH₂C₆H₃(OCH₂C₆H₅)2 
• 858127-48-7 C₅₈H₅₂O₇ 
• 811473-55-9 1-azidomethyl-3,5-bis(benzyloxy)benzene 

Relevant articles and documents

First example of a diazepinoporphyrazine with dendrimeric substituents

The synthesis and physicochemical properties of a novel diazepinoporphyrazine possessing G1-dendrimeric substituents are presented. Initially, diaminomaleonitrile was condensed with 1,3-bis-(4-hydroxyphenyl)-1,3-propanedione to give a novel 1,4-diazepine-

NOVEL FUNCTIONALIZED 1,3-BENZENE DIOLS AND THEIR METHOD OF USE FOR THE TREATMENT OF HEPATIC ENCEPHALOPTHY

Pharmaceutical compositions of the invention include novel functionalized 1,3-benzenediols having a disease-modifying action in the treatment of hepatic encephalopathy and related conditions. Pharmaceutical compositions of the invention further include novel neuroprotective agents.

NOVEL FUNCTIONALIZED 1,3-BENZENE DIOLS AND THEIR METHOD OF USE FOR THE TREATMENT OF HEPATIC ENCEPHALOPATHY

Pharmaceutical compositions of the invention include novel functionalized 1,3-benzenediols having a disease-modifying action in the treatment of hepatic encephalopathy and related conditions. Pharmaceutical compositions of the invention further include novel neuroprotective agents.