3-Hydroxy-3-(p-methoxyphenyl)-1-hexen

Base Information

• Chemical Name: 3-Hydroxy-3-(p-methoxyphenyl)-1-hexen
• CAS No.: 31254-22-5
• Molecular Formula: C₁₃H₁₈O₂
• Molecular Weight: 206.285
• Mol file: 31254-22-5.mol

Synonyms:3-Hydroxy-3-(p-methoxyphenyl)-1-hexen

Chemical Property of 3-Hydroxy-3-(p-methoxyphenyl)-1-hexen

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Hydroxy-3-(p-methoxyphenyl)-1-hexen

There total 2 articles about 3-Hydroxy-3-(p-methoxyphenyl)-1-hexen which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Vinyl bromide (593-60-2,25951-54-6) + 1-(4-methoxyphenyl)-1-butanone (4160-51-4) → 3-Hydroxy-3-(p-methoxyphenyl)-1-hexen (31254-22-5)

Guidance literature:

Multistep reaction; (i) Mg, Et₂O, (ii) /BRN= 908286/;

DOI:10.1021/jm00243a013

Reference yield:

→ 3-Hydroxy-3-(p-methoxyphenyl)-1-hexen (31254-22-5)

Guidance literature:

Propyl-aethinyl-anisyl-carbinol, H2;

DOI:10.1007/BF00852045

Reference yield:

3-Hydroxy-3-(p-methoxyphenyl)-1-hexen (31254-22-5) → 2β-Aethyl-3β-(p-hydroxyphenyl)-6β-methyl-trans-bicyclo<4.3.0>nonan-7β-ol

Guidance literature:

Multi-step reaction with 6 steps

2: KOH / propan-2-ol

3: TsOH / benzene

4: NaBH₄ / ethanol

5: H₂ / Pd-C / ethanol

6: KOH, N₂H₄ / bis-(2-hydroxy-ethyl) ether

With potassium hydroxide; sodium tetrahydroborate; hydrogen; toluene-4-sulfonic acid; hydrazine; palladium on activated charcoal; In ethanol; isopropyl alcohol; diethylene glycol; benzene;

DOI:10.1021/jm00243a013

upstream raw materials:

Vinyl bromide

1-(4-methoxyphenyl)-1-butanone

Downstream raw materials:

S-<3-(p-Methoxyphenyl)hexen-(2)-yl>isothiuroniumacetat

2-Methyl-2-<3-(p-methoxyphenyl)-2-hexenyl>-cyclopentan-1.3-dion

3-methoxy-5,6-secoestra-1,3,5⁽¹⁰⁾,8,14-pentaen-17-one