C₁₀H₁₂FNO

Base Information

Chemical Name:C₁₀H₁₂FNO
CAS No.:1568065-05-3
Molecular Formula:C₁₀H₁₂FNO
Molecular Weight:181.21
Hs Code.:

Synonyms:C₁₀H₁₂FNO

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₁₀H₁₂FNO

Chemical Property:

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Technology Process of C₁₀H₁₂FNO

There total 3 articles about C₁₀H₁₂FNO which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 455-36-7
1-(3-fluorophenyl)ethanone

: 1568065-05-3
C₁₀H₁₂FNO

Guidance literature:: Multi-step reaction with 2 steps

1: pyridoxal 5'-phosphate; isopropylamine / dimethyl sulfoxide / 24 h / 30 °C / pH 7.5 / Enzymatic reaction

2: potassium carbonate / ethyl acetate / 1 h / 30 °C

With pyridoxal 5'-phosphate; potassium carbonate; isopropylamine; In dimethyl sulfoxide; ethyl acetate;
DOI:10.1021/op4003104

Reference yield:

: 761390-58-3,444643-09-8
(R)-(-)-1-(3-fluorophenyl)ethylamine

: 108-24-7
acetic anhydride

: 1568065-05-3
C₁₀H₁₂FNO

Guidance literature:: With potassium carbonate; In ethyl acetate; at 30 ℃; for 1h;
DOI:10.1021/op4003104 DOI:10.1039/c6gc01981a

Reference yield:

: 402-63-1
1-(3-fluorophenyl)ethanol

: 1568065-05-3
C₁₀H₁₂FNO

Guidance literature:: Multi-step reaction with 3 steps

1: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; Trametes versicolor laccase / tert-butyl methyl ether / 16 h / 30 °C / pH 5 / Enzymatic reaction

2: isopropylamine; pyridoxal 5'-phosphate; transaminase ATA-033 / aq. phosphate buffer; dimethyl sulfoxide / 24 h / 30 °C / pH 7.5 / Enzymatic reaction

3: potassium carbonate / ethyl acetate / 1 h / 30 °C

With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; Trametes versicolor laccase; pyridoxal 5'-phosphate; transaminase ATA-033; potassium carbonate; isopropylamine; In aq. phosphate buffer; tert-butyl methyl ether; dimethyl sulfoxide; ethyl acetate;
DOI:10.1039/c6gc01981a