Frescolat

Base Information

Chemical Name:Frescolat
CAS No.:59259-38-0
Molecular Formula:C₁₃H₂₄O₃
Molecular Weight:228.332
Hs Code.:29181100
European Community (EC) Number:261-678-3
UNII:XFS8QYW6WY
DSSTox Substance ID:DTXSID601315646
Nikkaji Number:J2.067.184J
RXCUI:1866625
Mol file:59259-38-0.mol

Synonyms:l-menthyl lactate

Suppliers and Price of Frescolat

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
L-Menthyl lactate
10g
$ 75.00

Crysdot
(R)-(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl2-hydroxypropanoate 97%
100g
$ 49.00

American Custom Chemicals Corporation
(-)-MENTHYL LACTATE 95.00%
25G
$ 1178.86

American Custom Chemicals Corporation
(-)-MENTHYL LACTATE 95.00%
5G
$ 813.27

AK Scientific
L-Menthyl lactate
100g
$ 45.00

AHH
(-)-Menthyllactate 98%
1000g
$ 418.00

Total 107 raw suppliers

Chemical Property of Frescolat

Chemical Property:

Appearance/Colour:white to light yellow crystal powder
Vapor Pressure:8.58E-05mmHg at 25°C
Melting Point:40 °C
Refractive Index:-80 ° (C=5, MeOH)
Boiling Point:304 °C at 760 mmHg
PKA:13.01±0.20(Predicted)
Flash Point:116 °C
PSA：46.53000
Density:0.99 g/cm³
LogP:2.37120
Storage Temp.:2-8°C
Water Solubility.:SLIGHTLY SOLUBLE
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:228.17254462
Heavy Atom Count:16
Complexity:237

Purity/Quality:

99% ^*data from raw suppliers

L-Menthyl lactate ^*data from reagent suppliers

Safty Information:

Pictogram(s): T
Hazard Codes:T
Statements: 25
Safety Statements: 24/25-45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CCC(C(C1)OC(=O)C(C)O)C(C)C
Isomeric SMILES:C[C@@H]1CC[C@H]([C@@H](C1)OC(=O)[C@@H](C)O)C(C)C
Description L-Menthyl lactate has a weak odor somewhat reminiscent of tobacco and chamomile. It is almost tasteless, with a lasting gentle cooling effect.
Uses L-Menthyl Lactate is used in preparation of amides for generating a trigeminal sensory effect.

Technology Process of Frescolat

There total 3 articles about Frescolat which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 951-98-4
2-Oxo-propionic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester

: 17162-29-7,61597-98-6,59259-38-0,185915-25-7
(-)-menthyl lactate

Guidance literature:: With 1-naphthylphenylsilane; Rh catalyst; In benzene;
DOI:10.1021/jo00430a001

Reference yield:

: 951-98-4
2-Oxo-propionic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester

: 61597-98-6,185915-25-7
(1R,2S,5R)-menthyl (S)-(-)-lactate

: 17162-29-7,61597-98-6,59259-38-0,185915-25-7
(-)-menthyl lactate

Guidance literature:: With LiAlH; In tetrahydrofuran; at -78 ℃; for 3h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
DOI:10.1016/S0957-4166(00)80456-5

Reference yield:

: 29066-36-2,68539-56-0,86014-82-6,109716-85-0,127471-65-2,141552-99-0,141553-01-7,4951-48-8
(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl propionate

: 61597-98-6,185915-25-7
(1R,2S,5R)-menthyl (S)-(-)-lactate

: 17162-29-7,61597-98-6,59259-38-0,185915-25-7
(-)-menthyl lactate

Guidance literature:: With MoO₅*pyridine*HMPA; lithium diisopropyl amide; Yield given. Multistep reaction. Yields of byproduct given; 1.) THF, hexane, 2.) THF, hexane;
DOI:10.1016/S0957-4166(00)86253-9