(1,2-benzisoxazol-3-yl)methyl phenyl sulfoxide

Base Information

• Chemical Name: (1,2-benzisoxazol-3-yl)methyl phenyl sulfoxide
• CAS No.: 82897-94-7
• Molecular Formula: C₁₄H₁₁NO₂S
• Molecular Weight: 257.313
• Mol file: 82897-94-7.mol

Synonyms:(1,2-benzisoxazol-3-yl)methyl phenyl sulfoxide

Chemical Property of (1,2-benzisoxazol-3-yl)methyl phenyl sulfoxide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1,2-benzisoxazol-3-yl)methyl phenyl sulfoxide

There total 4 articles about (1,2-benzisoxazol-3-yl)methyl phenyl sulfoxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-Phenylsulfanylmethyl-benzo[d]isoxazole (82897-92-5) → (1,2-benzisoxazol-3-yl)methyl phenyl sulfoxide (82897-94-7)

Guidance literature:

With N-Bromosuccinimide; In tetrahydrofuran; water; for 0.5h; Yield given; Ambient temperature;

Reference yield:

α-bromo-1,2-benzisoxazole-3-acetic acid (37924-67-7) → (1,2-benzisoxazol-3-yl)methyl phenyl sulfoxide (82897-94-7)

Guidance literature:

Multi-step reaction with 3 steps

1: NaOH / aq. ethanol / 1 h / Ambient temperature

2: 0.33 h / 120 - 130 °C

3: N-bromosuccinimide / tetrahydrofuran; H₂O / 0.5 h / Ambient temperature

With sodium hydroxide; N-Bromosuccinimide; In tetrahydrofuran; ethanol; water;

Reference yield:

sodium thiophenolate (930-69-8) → (1,2-benzisoxazol-3-yl)methyl phenyl sulfoxide (82897-94-7)

Guidance literature:

Multi-step reaction with 3 steps

1: NaOH / aq. ethanol / 1 h / Ambient temperature

2: 0.33 h / 120 - 130 °C

3: N-bromosuccinimide / tetrahydrofuran; H₂O / 0.5 h / Ambient temperature

With sodium hydroxide; N-Bromosuccinimide; In tetrahydrofuran; ethanol; water;

upstream raw materials:

3-Phenylsulfanylmethyl-benzo[d]isoxazole

α-bromo-1,2-benzisoxazole-3-acetic acid

sodium thiophenolate

(1,2-benzisoxazol-3-yl)(phenylthio)acetic acid

Downstream raw materials:

C₁₄H₁₁ClN₂O₂S

C₁₄H₁₁BrN₂O₂S

N-bromo-S-phenyl-S<(1,2-benzisoxazol-3-yl)methyl>sulfoximide

C₁₄H₁₁ClN₂O₂S