10-hydroxy-10-(2-methoxymethoxyphenyl)-1,4,5,8-tetramethylanthrone

Base Information

• Chemical Name: 10-hydroxy-10-(2-methoxymethoxyphenyl)-1,4,5,8-tetramethylanthrone
• CAS No.: 439146-34-6
• Molecular Formula: C₂₆H₂₆O₄
• Molecular Weight: 402.49
• Mol file: 439146-34-6.mol

Synonyms:10-hydroxy-10-(2-methoxymethoxyphenyl)-1,4,5,8-tetramethylanthrone

Chemical Property of 10-hydroxy-10-(2-methoxymethoxyphenyl)-1,4,5,8-tetramethylanthrone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 10-hydroxy-10-(2-methoxymethoxyphenyl)-1,4,5,8-tetramethylanthrone

There total 2 articles about 10-hydroxy-10-(2-methoxymethoxyphenyl)-1,4,5,8-tetramethylanthrone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

O-methoxymethylphenol (824-91-9) + 1,4,5,8-tetramethylanthraquinone (17538-63-5) → 10-hydroxy-10-(2-methoxymethoxyphenyl)-1,4,5,8-tetramethylanthrone (439146-34-6)

Guidance literature:

O-methoxymethylphenol; With n-butyllithium; In diethyl ether;

1,4,5,8-tetramethylanthraquinone; In tetrahydrofuran; diethyl ether; at 20 ℃; for 1h;

DOI:10.1021/ja0518171

Reference yield:

phenol (108-95-2,27073-41-2) → 10-hydroxy-10-(2-methoxymethoxyphenyl)-1,4,5,8-tetramethylanthrone (439146-34-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: Na / tetrahydrofuran / Heating

1.2: 239.6 g / tetrahydrofuran / 1 h

2.1: BuLi / diethyl ether

2.2: 85 percent / tetrahydrofuran; diethyl ether / 1 h / 20 °C

With n-butyllithium; sodium; In tetrahydrofuran; diethyl ether;

DOI:10.1021/ja0518171

Reference yield: 88.4%

10-hydroxy-10-(2-methoxymethoxyphenyl)-1,4,5,8-tetramethylanthrone (439146-34-6) → 2-(9-(1,4,5,8-tetramethylanthracenyl))phenol

Guidance literature:

With lithium aluminium tetrahydride; boron trifluoride diethyl etherate; In diethyl ether; for 4h; Heating;

DOI:10.1021/ja0518171

upstream raw materials:

O-methoxymethylphenol

1,4,5,8-tetramethylanthraquinone

phenol

Refernces