2-[1-Benzotriazol-1-yl-1-phenyl-meth-(E)-ylidene]-3,3-dimethyl-butyraldehyde

Base Information

• Chemical Name: 2-[1-Benzotriazol-1-yl-1-phenyl-meth-(E)-ylidene]-3,3-dimethyl-butyraldehyde
• CAS No.: 627088-12-4
• Molecular Formula: C₁₉H₁₉N₃O
• Molecular Weight: 305.379
• Mol file: 627088-12-4.mol

Synonyms:2-[1-Benzotriazol-1-yl-1-phenyl-meth-(E)-ylidene]-3,3-dimethyl-butyraldehyde

Chemical Property of 2-[1-Benzotriazol-1-yl-1-phenyl-meth-(E)-ylidene]-3,3-dimethyl-butyraldehyde

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-[1-Benzotriazol-1-yl-1-phenyl-meth-(E)-ylidene]-3,3-dimethyl-butyraldehyde

There total 3 articles about 2-[1-Benzotriazol-1-yl-1-phenyl-meth-(E)-ylidene]-3,3-dimethyl-butyraldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

3-(benzotriazol-1-yl)-2-(tert-butyl)-3-phenyl-2-propenol (627088-05-5) → 2-[1-Benzotriazol-1-yl-1-phenyl-meth-(E)-ylidene]-3,3-dimethyl-butyraldehyde (627088-12-4)

Guidance literature:

3-(benzotriazol-1-yl)-2-(tert-butyl)-3-phenyl-2-propenol; With oxalyl dichloride; dimethyl sulfoxide; In dichloromethane; at -78 ℃;

With triethylamine; In dichloromethane; at -78 ℃; for 2h;

DOI:10.1016/j.tetlet.2003.08.012

Reference yield:

1-benzyl-1H-benzotriazole (4706-43-8) → 2-[1-Benzotriazol-1-yl-1-phenyl-meth-(E)-ylidene]-3,3-dimethyl-butyraldehyde (627088-12-4)

Guidance literature:

Multi-step reaction with 3 steps

1.1: n-BuLi / tetrahydrofuran / -78 °C

1.2: tetrahydrofuran

2.1: n-BuLi / tetrahydrofuran / -78 °C

2.2: H₃O⁽¹⁺⁾

3.1: DMSO; oxalyl chloride / CH₂Cl₂ / -78 °C

3.2: 64 percent / triethylamine / CH₂Cl₂ / 2 h / -78 °C

With n-butyllithium; oxalyl dichloride; dimethyl sulfoxide; In tetrahydrofuran; dichloromethane;

DOI:10.1016/j.tetlet.2003.08.012

Reference yield:

1-[(2-tert-butyl-oxiranyl)-phenyl-methyl]-1H-benzotriazole → 2-[1-Benzotriazol-1-yl-1-phenyl-meth-(E)-ylidene]-3,3-dimethyl-butyraldehyde (627088-12-4)

Guidance literature:

Multi-step reaction with 2 steps

1.1: n-BuLi / tetrahydrofuran / -78 °C

1.2: H₃O⁽¹⁺⁾

2.1: DMSO; oxalyl chloride / CH₂Cl₂ / -78 °C

2.2: 64 percent / triethylamine / CH₂Cl₂ / 2 h / -78 °C

With n-butyllithium; oxalyl dichloride; dimethyl sulfoxide; In tetrahydrofuran; dichloromethane;

DOI:10.1016/j.tetlet.2003.08.012

upstream raw materials:

3-(benzotriazol-1-yl)-2-(tert-butyl)-3-phenyl-2-propenol

1-benzyl-1H-benzotriazole

Downstream raw materials:

(E)-3-(benzotriazol-1-yl)-2-(t-butyl)-1-(naphthalen-1-yl)-3-phenylprop-2-en-1-ol

(E)-3-(benzotriazol-1-yl)-2-(t-butyl)-1,3-diphenylprop-2-en-1-ol

(E)-3-(benzotriazol-1-yl)-2-(t-butyl)-3-phenyl-1-(thiophen-2-yl)prop-2-en-1-ol

C₂₇H₂₃F₃N₄O