N-(((4-bromo-3-(4-methoxyphenyl)isoquinolin-1-yl)(4-chlorophenyl)amino)(4-chlorophenylamino)methylene)-4-methylbenzenesulfonamide

Base Information

Chemical Name:N-(((4-bromo-3-(4-methoxyphenyl)isoquinolin-1-yl)(4-chlorophenyl)amino)(4-chlorophenylamino)methylene)-4-methylbenzenesulfonamide
CAS No.:1383274-35-8
Molecular Formula:C₃₆H₂₇BrCl₂N₄O₃S
Molecular Weight:746.511
Hs Code.:

Synonyms:N-(((4-bromo-3-(4-methoxyphenyl)isoquinolin-1-yl)(4-chlorophenyl)amino)(4-chlorophenylamino)methylene)-4-methylbenzenesulfonamide

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Chemical Property of N-(((4-bromo-3-(4-methoxyphenyl)isoquinolin-1-yl)(4-chlorophenyl)amino)(4-chlorophenylamino)methylene)-4-methylbenzenesulfonamide

Chemical Property:

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Technology Process of N-(((4-bromo-3-(4-methoxyphenyl)isoquinolin-1-yl)(4-chlorophenyl)amino)(4-chlorophenylamino)methylene)-4-methylbenzenesulfonamide

There total 3 articles about N-(((4-bromo-3-(4-methoxyphenyl)isoquinolin-1-yl)(4-chlorophenyl)amino)(4-chlorophenylamino)methylene)-4-methylbenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 838-98-2
bis-(4-chloro-phenyl)-carbodiimide

: C₂₃H₁₉BrN₂O₃S

: 1383274-35-8
N-(((4-bromo-3-(4-methoxyphenyl)isoquinolin-1-yl)(4-chlorophenyl)amino)(4-chlorophenylamino)methylene)-4-methylbenzenesulfonamide

Guidance literature:: In dichloromethane; acetonitrile; at 20 ℃;
DOI:10.1016/j.tet.2012.03.081

Reference yield:

: 1174271-10-3
C₂₃H₂₀N₂O₃S

: 1383274-35-8
N-(((4-bromo-3-(4-methoxyphenyl)isoquinolin-1-yl)(4-chlorophenyl)amino)(4-chlorophenylamino)methylene)-4-methylbenzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: 1,4-diaza-bicyclo[2.2.2]octane; bromine / dichloromethane / 0.17 h / 20 °C

2: dichloromethane; acetonitrile / 20 °C

With 1,4-diaza-bicyclo[2.2.2]octane; bromine; In dichloromethane; acetonitrile;
DOI:10.1016/j.tet.2012.03.081

Reference yield:

: 176910-67-1
2-(4-methoxyphenylethynyl)benzaldehyde

: 1383274-35-8
N-(((4-bromo-3-(4-methoxyphenyl)isoquinolin-1-yl)(4-chlorophenyl)amino)(4-chlorophenylamino)methylene)-4-methylbenzenesulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1: dichloromethane / 0.5 h / 20 °C

2: 1,4-diaza-bicyclo[2.2.2]octane; bromine / dichloromethane / 0.17 h / 20 °C

3: dichloromethane; acetonitrile / 20 °C

With 1,4-diaza-bicyclo[2.2.2]octane; bromine; In dichloromethane; acetonitrile;
DOI:10.1016/j.tet.2012.03.081