methyl 2-fluoro-2-phenylsulfanylacetate

Base Information

• Chemical Name: methyl 2-fluoro-2-phenylsulfanylacetate
• CAS No.: 109705-27-3
• Molecular Formula: C₉H₉FO₂S
• Molecular Weight: 200.234
• Mol file: 109705-27-3.mol

Synonyms:methyl 2-fluoro-2-phenylsulfanylacetate

Chemical Property of methyl 2-fluoro-2-phenylsulfanylacetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2-fluoro-2-phenylsulfanylacetate

There total 7 articles about methyl 2-fluoro-2-phenylsulfanylacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

methyl (phenylsulfanyl)acetate (17277-58-6) → methyl 2-fluoro-2-phenylsulfanylacetate (109705-27-3)

Guidance literature:

With triethylamine tris(hydrogen fluoride); In acetonitrile; at 25 ℃; electrochemical reaction: Pt wire as working electrode, Pt foil counter electrode and Pd/H₂ reference electrode;

DOI:10.1016/S0022-1139(98)00267-X

Reference yield: 66.0%

methyl 2-chloro-2-(phenylsulfanyl)acetate (85920-99-6) → methyl 2-fluoro-2-phenylsulfanylacetate (109705-27-3)

Guidance literature:

With triethylamine tris(hydrogen fluoride); zinc dibromide; In acetonitrile; for 18h; Heating;

DOI:10.1016/S0040-4020(98)00639-5

Reference yield:

methyl (phenylsulfanyl)acetate (17277-58-6) → Difluor-S-phenyl-thioglykolsaeure-methylester (22340-44-9) + methyl 2-fluoro-2-phenylsulfanylacetate (109705-27-3)

Guidance literature:

With triethylamine tris(hydrogen fluoride); In acetonitrile; at 25 ℃; electrolyse: Pt anode and cathode, average cell voltage: 3.80 V, charge: 2F + 0.4F/mol;

DOI:10.1016/S0022-1139(98)00279-6

upstream raw materials:

methyl (phenylsulfanyl)acetate

1-fluoro-2,4,6-trimethylpyridinium trifluoromethanesulfonate

methyl chlorofluoroacetate

thiophenol

Downstream raw materials:

Benzenesulfinyl-fluoro-acetic acid methyl ester