DIFLUORO-PHENYLSULFANYL-ACETIC ACID METHYL ESTER

Base Information

• Chemical Name: DIFLUORO-PHENYLSULFANYL-ACETIC ACID METHYL ESTER
• CAS No.: 22340-44-9
• Molecular Formula: C₉H₈F₂O₂S
• Molecular Weight: 218.224
• Mol file: 22340-44-9.mol

Synonyms:DIFLUORO-PHENYLSULFANYL-ACETIC ACID METHYL ESTER;METHYL DIFLUORO(PHENYLSULFANYL)ACETATE

Chemical Property of DIFLUORO-PHENYLSULFANYL-ACETIC ACID METHYL ESTER

Chemical Property:

• Vapor Pressure: 0.0984mmHg at 25°C
• Boiling Point: 223°C at 760 mmHg
• Flash Point: 88.7°C
• Density: 1.3g/cm³

Purity/Quality:

DIFLUORO-PHENYLSULFANYL ACETIC ACID METHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of DIFLUORO-PHENYLSULFANYL-ACETIC ACID METHYL ESTER

There total 2 articles about DIFLUORO-PHENYLSULFANYL-ACETIC ACID METHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl (phenylsulfanyl)acetate (17277-58-6) → Difluor-S-phenyl-thioglykolsaeure-methylester (22340-44-9) + methyl 2-fluoro-2-phenylsulfanylacetate (109705-27-3)

Guidance literature:

With triethylamine tris(hydrogen fluoride); In acetonitrile; at 25 ℃; electrolyse: Pt anode and cathode, average cell voltage: 3.80 V, charge: 2F + 0.4F/mol;

DOI:10.1016/S0022-1139(98)00279-6

Reference yield:

methanol (67-56-1) + Difluor-phenylmercapto-acetylchlorid (16503-77-8) → Difluor-S-phenyl-thioglykolsaeure-methylester (22340-44-9)

Guidance literature:

With triethylamine; In benzene;

Reference yield:

Difluor-S-phenyl-thioglykolsaeure-methylester (22340-44-9) → Difluor-phenylsulfonyl-essigsaeure-amid (22235-35-4)

Guidance literature:

Multi-step reaction with 2 steps

1: CrO₃, AcOH

2: NH₃ / diethyl ether

With chromium(VI) oxide; ammonia; acetic acid; In diethyl ether;

upstream raw materials:

methanol

Difluor-phenylmercapto-acetylchlorid

methyl (phenylsulfanyl)acetate

Downstream raw materials:

Difluor-phenylsulfonyl-essigsaeure-methylester

Difluor-phenylsulfonyl-essigsaeure-amid

phenylsulfonyldifluoroacetic acid

Refernces