(3R,4R)-3,4-dimethoxy-1-{[(3R,4R)-3,4-dimethoxy-1-(benzyloxycarbonylamino)-cyclopentyl]carbonylamino}cyclopentanecarboxylic acid

Base Information

Chemical Name:(3R,4R)-3,4-dimethoxy-1-{[(3R,4R)-3,4-dimethoxy-1-(benzyloxycarbonylamino)-cyclopentyl]carbonylamino}cyclopentanecarboxylic acid
CAS No.:1380078-03-4
Molecular Formula:C₂₄H₃₄N₂O₉
Molecular Weight:494.542
Hs Code.:

Synonyms:(3R,4R)-3,4-dimethoxy-1-{[(3R,4R)-3,4-dimethoxy-1-(benzyloxycarbonylamino)-cyclopentyl]carbonylamino}cyclopentanecarboxylic acid

Suppliers and Price of (3R,4R)-3,4-dimethoxy-1-{[(3R,4R)-3,4-dimethoxy-1-(benzyloxycarbonylamino)-cyclopentyl]carbonylamino}cyclopentanecarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3R,4R)-3,4-dimethoxy-1-{[(3R,4R)-3,4-dimethoxy-1-(benzyloxycarbonylamino)-cyclopentyl]carbonylamino}cyclopentanecarboxylic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3R,4R)-3,4-dimethoxy-1-{[(3R,4R)-3,4-dimethoxy-1-(benzyloxycarbonylamino)-cyclopentyl]carbonylamino}cyclopentanecarboxylic acid

There total 9 articles about (3R,4R)-3,4-dimethoxy-1-{[(3R,4R)-3,4-dimethoxy-1-(benzyloxycarbonylamino)-cyclopentyl]carbonylamino}cyclopentanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1380078-02-3
methyl (3R,4R)-3,4-dimethoxy-1-{[(3R,4R)-3,4-dimethoxy-1-(benzyloxycarbonylamino)-cyclopentyl]carbonylamino}cyclopentanecarboxylate

: 1380078-03-4
(3R,4R)-3,4-dimethoxy-1-{[(3R,4R)-3,4-dimethoxy-1-(benzyloxycarbonylamino)-cyclopentyl]carbonylamino}cyclopentanecarboxylic acid

Guidance literature:: methyl (3R,4R)-3,4-dimethoxy-1-{[(3R,4R)-3,4-dimethoxy-1-(benzyloxycarbonylamino)-cyclopentyl]carbonylamino}cyclopentanecarboxylate; With sodium hydroxide; In methanol; water; at 20 ℃; for 12h;

With hydrogenchloride; In methanol; water;
DOI:10.1002/chem.201102902

Reference yield:

: C₁₀H₁₅NO₅

: 1380078-03-4
(3R,4R)-3,4-dimethoxy-1-{[(3R,4R)-3,4-dimethoxy-1-(benzyloxycarbonylamino)-cyclopentyl]carbonylamino}cyclopentanecarboxylic acid

Guidance literature:: Multi-step reaction with 4 steps

1: benzene / 6 h / Reflux

2: sodium hydroxide / methanol; water / 12 h / 20 °C

3: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / acetonitrile / 60 h / 20 °C

4: sodium hydroxide / methanol; water / 12 h / 20 °C

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; sodium hydroxide; In methanol; water; acetonitrile; benzene;
DOI:10.1002/chem.201102902

Reference yield:

: 1380078-00-1
methyl (3R,4R)-1-benzyloxycarbonylamino-3,4-(dimethoxy)cyclopentanecarboxylate

: 1380078-03-4
(3R,4R)-3,4-dimethoxy-1-{[(3R,4R)-3,4-dimethoxy-1-(benzyloxycarbonylamino)-cyclopentyl]carbonylamino}cyclopentanecarboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 5%-palladium/activated carbon; hydrogen / methanol / 12 h

2: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / acetonitrile / 60 h / 20 °C

3: sodium hydroxide / methanol; water / 12 h / 20 °C

With 5%-palladium/activated carbon; hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; sodium hydroxide; In methanol; water; acetonitrile;
DOI:10.1002/chem.201102902