Technology Process of 1-(2,6-dimethyl-3,4-dihydro-2H-pyran-2-yl)-ethanone
There total 1 articles about 1-(2,6-dimethyl-3,4-dihydro-2H-pyran-2-yl)-ethanone which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sodium amide;
Yield given. Multistep reaction;
1) ether, 45 min 2) ether, 24h, reflux;
DOI:10.1016/S0040-4020(01)81519-2
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1) NaH, EtOH, ethyl formate 2) mesyl azide / 1) ether a) 3.5h, -5 deg C b) 18h, 20 deg C 2) ether, 3.5d
2: 88 percent / K2CO3 / 2 / CH2Cl2 / 2 h / Ambient temperature
3: 1) Mg, Cu2I2 / 1) ether, THF, -25 deg C 2) a) -75 deg C, 30 min b) -5 deg C to 0 deg C, 4.5h
4: 9 percent / N2H4*H2O, K2CO3 / various solvent(s) / Heating
With
copper (I) iodide; ethanol; sodium hydride; potassium carbonate; hydrazine hydrate; magnesium; Methanesulfonyl azide; formic acid ethyl ester;
dirhodium tetraacetate;
In
dichloromethane;
DOI:10.1016/S0040-4020(01)81519-2
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1) EtONa, (CO2Et)2, 2) TsN3 / 1) EtOH, 24 h, 2) 12 h
2: 92 percent / 2 / CH2Cl2 / 0.08 h / Ambient temperature
3: 45 percent / BF3*Et2O / 1) -78 deg C, 45min, 2) 0 deg C, 30 min
With
4-toluenesulfonyl azide; boron trifluoride diethyl etherate; sodium ethanolate; oxalic acid diethyl ester;
dirhodium tetraacetate;
In
dichloromethane;
DOI:10.1016/S0040-4039(00)84452-4
