(Z)-2-(3,3,3-trifluoro-2-oxo-1-(4-(trifluoromethyl)phenyl)propylidene)-1H-indene-1,3(2H)-dione

Base Information

• Chemical Name: (Z)-2-(3,3,3-trifluoro-2-oxo-1-(4-(trifluoromethyl)phenyl)propylidene)-1H-indene-1,3(2H)-dione
• CAS No.: 1607832-20-1
• Molecular Formula: C₁₉H₈F₆O₃
• Molecular Weight: 398.261

Synonyms:(Z)-2-(3,3,3-trifluoro-2-oxo-1-(4-(trifluoromethyl)phenyl)propylidene)-1H-indene-1,3(2H)-dione

Chemical Property of (Z)-2-(3,3,3-trifluoro-2-oxo-1-(4-(trifluoromethyl)phenyl)propylidene)-1H-indene-1,3(2H)-dione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z)-2-(3,3,3-trifluoro-2-oxo-1-(4-(trifluoromethyl)phenyl)propylidene)-1H-indene-1,3(2H)-dione

There total 3 articles about (Z)-2-(3,3,3-trifluoro-2-oxo-1-(4-(trifluoromethyl)phenyl)propylidene)-1H-indene-1,3(2H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

(E)-2-(4-(trifluoromethyl)benzylidene)-1H-indene-1,3(2H)-dione (178697-87-5) + trifluoroacetic anhydride (407-25-0) → (Z)-2-(3,3,3-trifluoro-2-oxo-1-(4-(trifluoromethyl)phenyl)propylidene)-1H-indene-1,3(2H)-dione (1607832-20-1)

Guidance literature:

With triethylamine; ethyl-diphenyl-phosphane; In tetrahydrofuran; at 27 - 30 ℃; for 0.166667h; Mechanism; Inert atmosphere; Schlenk technique;

DOI:10.1039/c3cc45201h

Reference yield:

1H-indene-1,3(2H)-dione (606-23-5) → (Z)-2-(3,3,3-trifluoro-2-oxo-1-(4-(trifluoromethyl)phenyl)propylidene)-1H-indene-1,3(2H)-dione (1607832-20-1)

Guidance literature:

Multi-step reaction with 2 steps

1: L-proline / methanol / 12 h / 27 - 30 °C / Schlenk technique

2: triethylamine; ethyl-diphenyl-phosphane / tetrahydrofuran / 0.17 h / 27 - 30 °C / Inert atmosphere; Schlenk technique

With triethylamine; ethyl-diphenyl-phosphane; L-proline; In tetrahydrofuran; methanol;

DOI:10.1039/c3cc45201h

Reference yield:

4-Trifluoromethylbenzaldehyde (455-19-6) → (Z)-2-(3,3,3-trifluoro-2-oxo-1-(4-(trifluoromethyl)phenyl)propylidene)-1H-indene-1,3(2H)-dione (1607832-20-1)

Guidance literature:

Multi-step reaction with 2 steps

1: L-proline / methanol / 12 h / 27 - 30 °C / Schlenk technique

2: triethylamine; ethyl-diphenyl-phosphane / tetrahydrofuran / 0.17 h / 27 - 30 °C / Inert atmosphere; Schlenk technique

With triethylamine; ethyl-diphenyl-phosphane; L-proline; In tetrahydrofuran; methanol;

DOI:10.1039/c3cc45201h

upstream raw materials:

(E)-2-(4-(trifluoromethyl)benzylidene)-1H-indene-1,3(2H)-dione

trifluoroacetic anhydride

1H-indene-1,3(2H)-dione

4-Trifluoromethylbenzaldehyde

Downstream raw materials:

3-(trifluoromethyl)-4-(4-(trifluoromethyl)phenyl)-5H-indeno[1,2-c]pyridazin-5-one

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1607832-20-1 (Z)-2-(3,3,3-trifluoro-2-oxo-1-(4-(trifluoromethyl)phenyl)propylidene)-1H-indene-1,3(2H)-dione

Send

Send

Metric Ton KG G Pound L ML

Send

Send