[(1,3-Benzodioxol-5-ylcarbonyl)amino]acetic acid

Base Information

Chemical Name:[(1,3-Benzodioxol-5-ylcarbonyl)amino]acetic acid
CAS No.:27855-25-0
Molecular Formula:C10H9 N O5
Molecular Weight:223.185
Hs Code.:2932999099
UNII:TV4TN3M5JL
Mol file:27855-25-0.mol

Synonyms:27855-25-0;[(1,3-benzodioxol-5-ylcarbonyl)amino]acetic acid;2-(1,3-benzodioxole-5-carbonylamino)acetic acid;3,4-methylenedioxyhippuric acid;TV4TN3M5JL;2-(Benzo[d][1,3]dioxole-5-carboxamido)acetic acid;2-(2H-1,3-benzodioxol-5-ylformamido)acetic acid;Glycine, N-(1,3-benzodioxol-5-ylcarbonyl)-;piperonylglycine;UNII-TV4TN3M5JL;SCHEMBL2788308;CHEBI:189769;HMS1729J03;CBA85525;MFCD00617653;AKOS000117161;3,4-METHYLENEDIOXYBENZOYLGLYCINE;(Benzo[d][1,3]dioxole-5-carbonyl)glycine;CS-0346254;2-(1,3-Dioxaindan-5-ylformamido)acetic acid;EN300-08096;2-[(1,3-dioxaindan-5-yl)formamido]acetic acid;N-(1,3-BENZODIOXOL-5-YLCARBONYL)GLYCINE;SR-01000044841;2-(Benzo[d][1,3]dioxole-5-carboxamido)aceticacid;SR-01000044841-1;((3,4-METHYLENEDIOXYBENZOYL)AMINO)ACETIC ACID;2-[(2H-1,3-benzodioxol-5-yl)formamido]acetic acid;Z56928563;2-{[(2H-1,3-benzodioxol-5-yl)(hydroxy)methylidene]amino}acetic acid

Suppliers and Price of [(1,3-Benzodioxol-5-ylcarbonyl)amino]acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(2H-1,3-benzodioxol-5-ylformamido)aceticAcid
500mg
$ 310.00

Crysdot
2-(Benzo[d][1,3]dioxole-5-carboxamido)aceticacid 97%
5g
$ 564.00

American Custom Chemicals Corporation
[(1,3-BENZODIOXOL-5-YLCARBONYL)AMINO]ACETIC ACID 95.00%
5G
$ 1082.56

American Custom Chemicals Corporation
[(1,3-BENZODIOXOL-5-YLCARBONYL)AMINO]ACETIC ACID 95.00%
2.5G
$ 906.27

American Custom Chemicals Corporation
[(1,3-BENZODIOXOL-5-YLCARBONYL)AMINO]ACETIC ACID 95.00%
1G
$ 677.91

AK Scientific
[(1,3-Benzodioxol-5-ylcarbonyl)amino]aceticacid
1g
$ 387.00

AK Scientific
[(1,3-Benzodioxol-5-ylcarbonyl)amino]aceticacid
250mg
$ 370.00

Total 3 raw suppliers

Chemical Property of [(1,3-Benzodioxol-5-ylcarbonyl)amino]acetic acid

Chemical Property:

Vapor Pressure:8.43E-09mmHg at 25°C
Boiling Point:447.7°Cat760mmHg
Flash Point:224.6°C
PSA：88.35000
Density:g/cm³
LogP:0.80450
XLogP3:0.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:223.04807239
Heavy Atom Count:16
Complexity:293

Purity/Quality:

99% ^*data from raw suppliers

2-(2H-1,3-benzodioxol-5-ylformamido)aceticAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1OC2=C(O1)C=C(C=C2)C(=O)NCC(=O)O

Technology Process of [(1,3-Benzodioxol-5-ylcarbonyl)amino]acetic acid

There total 7 articles about [(1,3-Benzodioxol-5-ylcarbonyl)amino]acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 76208-96-3
ethyl 2-(benzo[d][1,3]dioxole-5-carboxamido)acetate

: 27855-25-0
N-(benzo[1,3]dioxole-5-carbonyl)-glycine

Guidance literature:: With sodium hydroxide; In methanol; at 60 ℃;
DOI:10.1016/j.bioorg.2020.103749

Reference yield:

: 94-53-1
Piperonylic acid

: 27855-25-0
N-(benzo[1,3]dioxole-5-carbonyl)-glycine

Guidance literature:

Reference yield:

: 139-85-5
3,4-dihydroxybenzaldehyde

: 27855-25-0
N-(benzo[1,3]dioxole-5-carbonyl)-glycine

Guidance literature:: Multi-step reaction with 4 steps

1.1: copper(II) oxide / dichloromethane / Reflux

2.1: sodium hydroxide / 0.17 h

2.2: 80 °C

3.1: N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate / N,N-dimethyl-formamide / 2 h / 20 °C

3.2: 7 h

4.1: sodium hydroxide / methanol / 60 °C

With N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; copper(II) oxide; sodium hydroxide; In methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.bioorg.2020.103749