(2S)-2-{[3-(3'-[1,1'-biphenyl]-4-yl-4',5'-dihydro-5'-isoxazolyl)-2-{[hydroxyl(2-phenyl-(1R)-1-{[(benzyloxy)carbonyl]amino}ethyl)phosphinyl]methyl}-1-oxopropyl]amino}1H-indole-3-propanoic acid

Base Information

Chemical Name:(2S)-2-{[3-(3'-[1,1'-biphenyl]-4-yl-4',5'-dihydro-5'-isoxazolyl)-2-{[hydroxyl(2-phenyl-(1R)-1-{[(benzyloxy)carbonyl]amino}ethyl)phosphinyl]methyl}-1-oxopropyl]amino}1H-indole-3-propanoic acid
CAS No.:1198770-37-4
Molecular Formula:C₄₆H₄₅N₄O₈P
Molecular Weight:812.859
Hs Code.:

(2S)-2-{[3-(3'-[1,1'-biphenyl]-4-yl-4',5'-dihydro-5'-isoxazolyl)-2-{[hydroxyl(2-phenyl-(1R)-1-{[(benzyloxy)carbonyl]amino}ethyl)phosphinyl]methyl}-1-oxopropyl]amino}1H-indole-3-propanoic acid

Synonyms:(2S)-2-{[3-(3'-[1,1'-biphenyl]-4-yl-4',5'-dihydro-5'-isoxazolyl)-2-{[hydroxyl(2-phenyl-(1R)-1-{[(benzyloxy)carbonyl]amino}ethyl)phosphinyl]methyl}-1-oxopropyl]amino}1H-indole-3-propanoic acid

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Chemical Property of (2S)-2-{[3-(3'-[1,1'-biphenyl]-4-yl-4',5'-dihydro-5'-isoxazolyl)-2-{[hydroxyl(2-phenyl-(1R)-1-{[(benzyloxy)carbonyl]amino}ethyl)phosphinyl]methyl}-1-oxopropyl]amino}1H-indole-3-propanoic acid

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Technology Process of (2S)-2-{[3-(3'-[1,1'-biphenyl]-4-yl-4',5'-dihydro-5'-isoxazolyl)-2-{[hydroxyl(2-phenyl-(1R)-1-{[(benzyloxy)carbonyl]amino}ethyl)phosphinyl]methyl}-1-oxopropyl]amino}1H-indole-3-propanoic acid

There total 1 articles about (2S)-2-{[3-(3'-[1,1'-biphenyl]-4-yl-4',5'-dihydro-5'-isoxazolyl)-2-{[hydroxyl(2-phenyl-(1R)-1-{[(benzyloxy)carbonyl]amino}ethyl)phosphinyl]methyl}-1-oxopropyl]amino}1H-indole-3-propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 40143-27-9
biphenyl-4-carbaldehyde oxime

: C₃₃H₃₆N₃O₇P

: 1198770-37-4
(2S)-2-{[3-(3'-[1,1'-biphenyl]-4-yl-4',5'-dihydro-5'-isoxazolyl)-2-{[hydroxyl(2-phenyl-(1R)-1-{[(benzyloxy)carbonyl]amino}ethyl)phosphinyl]methyl}-1-oxopropyl]amino}1H-indole-3-propanoic acid

Guidance literature:: biphenyl-4-carbaldehyde oxime; With pyridine; N-chloro-succinimide; In chloroform; at 20 - 45 ℃;

C₃₃H₃₆N₃O₇P; With triethylamine; at 45 ℃;
DOI:10.1021/jm9010803