(6R,7R)-7-[(1-benzylpyridinium-4-yl)amino]-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

Base Information

Chemical Name:(6R,7R)-7-[(1-benzylpyridinium-4-yl)amino]-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
CAS No.:77527-71-0
Molecular Formula:C22H21N7O3S2
Molecular Weight:495.5772
Hs Code.:

(6R,7R)-7-[(1-benzylpyridinium-4-yl)amino]-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

Synonyms:4-[(2-carboxy-3-{[(1-methyl-1H-tetrazol-5-yl)thio]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-7β-yl)amino]-1-benzylpyridinium hydroxide inner salt;

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (6R,7R)-7-[(1-benzylpyridinium-4-yl)amino]-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

Chemical Property:

PSA：170.55000
LogP:0.04870

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (6R,7R)-7-[(1-benzylpyridinium-4-yl)amino]-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

There total 2 articles about (6R,7R)-7-[(1-benzylpyridinium-4-yl)amino]-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 77527-66-3
1-benzyl-4-fluoropyridinium bromide

: 24209-38-9
(6R,7R)-7-amino-3-[(1H-1-methyltetrazol-5-yl)thio]methylceph-3-em-4-carboxylic acid

: 77527-71-0
4-<<2-carboxy-3-<<(1-methyl-1H-tetrazol-5-yl)thio>methyl>-8-oxo-5-thia-1-azabicyclo<4.2.0>oct-2-en-7β-yl>amino>-1-benzylpyridinium hydroxide inner salt

Guidance literature:: With sodium hydroxide; In water; at 22 ℃; for 0.333333h; pH 8.5;
DOI:10.1021/jm00346a024

Reference yield:

: 80706-15-6
1-benzyl-4-chloropyridinium bromide

: 77527-71-0
4-<<2-carboxy-3-<<(1-methyl-1H-tetrazol-5-yl)thio>methyl>-8-oxo-5-thia-1-azabicyclo<4.2.0>oct-2-en-7β-yl>amino>-1-benzylpyridinium hydroxide inner salt

Guidance literature:: Multi-step reaction with 2 steps

1: KF / dimethylformamide / 2 h / 22 °C

2: 69 percent / 2.5 N NaOH / H₂O / 0.33 h / 22 °C / pH 8.5

With potassium fluoride; sodium hydroxide; In water; N,N-dimethyl-formamide;
DOI:10.1021/jm00346a024