N₁-(cyclohexylmethyl)-N₂-[3-fluoro-5-(hydroxymethyl)pyridin-2-yl]-D-valinamide

Base Information

Chemical Name:N₁-(cyclohexylmethyl)-N₂-[3-fluoro-5-(hydroxymethyl)pyridin-2-yl]-D-valinamide
CAS No.:1035217-10-7
Molecular Formula:C₁₈H₂₈FN₃O₂
Molecular Weight:337.438
Hs Code.:

N<sub>1</sub>-(cyclohexylmethyl)-N<sub>2</sub>-[3-fluoro-5-(hydroxymethyl)pyridin-2-yl]-D-valinamide

Synonyms:N₁-(cyclohexylmethyl)-N₂-[3-fluoro-5-(hydroxymethyl)pyridin-2-yl]-D-valinamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N₁-(cyclohexylmethyl)-N₂-[3-fluoro-5-(hydroxymethyl)pyridin-2-yl]-D-valinamide

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Technology Process of N₁-(cyclohexylmethyl)-N₂-[3-fluoro-5-(hydroxymethyl)pyridin-2-yl]-D-valinamide

There total 1 articles about N₁-(cyclohexylmethyl)-N₂-[3-fluoro-5-(hydroxymethyl)pyridin-2-yl]-D-valinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1035217-08-3
6-({(1R)-1-[(cyclohexylmethyl)carbamoyl]-2-methylpropyl}amino)-5-fluoronicotinic acid

: 1035217-10-7
N₁-(cyclohexylmethyl)-N₂-[3-fluoro-5-(hydroxymethyl)pyridin-2-yl]-D-valinamide

Guidance literature:: 6-({(1R)-1-[(cyclohexylmethyl)carbamoyl]-2-methylpropyl}amino)-5-fluoronicotinic acid; With 4-methyl-morpholine; isobutyl chloroformate; In 1,2-dimethoxyethane; at 0 ℃; for 0.5h;

With sodium tetrahydroborate; In 1,2-dimethoxyethane; water; at 0 - 20 ℃; for 1h;

With hydrogenchloride; water; pH=2;