1β,5β-bis(benzyloxy)-3β-<(tert-butyldimethylsilyl)oxy>-6α,7α-dihydroxy-2α,4α-dimethoxycycloheptane

Base Information

Chemical Name:1β,5β-bis(benzyloxy)-3β-<(tert-butyldimethylsilyl)oxy>-6α,7α-dihydroxy-2α,4α-dimethoxycycloheptane
CAS No.:142482-31-3
Molecular Formula:C₂₉H₄₄O₇Si
Molecular Weight:532.75
Hs Code.:

Synonyms:1β,5β-bis(benzyloxy)-3β-<(tert-butyldimethylsilyl)oxy>-6α,7α-dihydroxy-2α,4α-dimethoxycycloheptane

Suppliers and Price of 1β,5β-bis(benzyloxy)-3β-<(tert-butyldimethylsilyl)oxy>-6α,7α-dihydroxy-2α,4α-dimethoxycycloheptane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1β,5β-bis(benzyloxy)-3β-<(tert-butyldimethylsilyl)oxy>-6α,7α-dihydroxy-2α,4α-dimethoxycycloheptane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1β,5β-bis(benzyloxy)-3β-<(tert-butyldimethylsilyl)oxy>-6α,7α-dihydroxy-2α,4α-dimethoxycycloheptane

There total 5 articles about 1β,5β-bis(benzyloxy)-3β-<(tert-butyldimethylsilyl)oxy>-6α,7α-dihydroxy-2α,4α-dimethoxycycloheptane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 142458-32-0
5β-<(tert-butyldimethylsilyl)oxy>-3β,7β-bis(benzyloxy)-4α,6α-dimethoxycyclohept-1-ene

: 142482-31-3
1β,5β-bis(benzyloxy)-3β-<(tert-butyldimethylsilyl)oxy>-6α,7α-dihydroxy-2α,4α-dimethoxycycloheptane

Guidance literature:: With osmium(VIII) oxide; 4-methylmorpholine N-oxide; In tetrahydrofuran; water; acetone; for 5h; Ambient temperature;
DOI:10.1021/jo00040a043

Reference yield:

: 100-39-0
benzyl bromide

: 142482-31-3
1β,5β-bis(benzyloxy)-3β-<(tert-butyldimethylsilyl)oxy>-6α,7α-dihydroxy-2α,4α-dimethoxycycloheptane

Guidance literature:: Multi-step reaction with 2 steps

1: 91.6 percent / NaH, Bu₄NI / tetrahydrofuran / 12 h / Ambient temperature

2: 87 percent / OsO₄, N-methylmorpholine N-oxide / acetone; H₂O; tetrahydrofuran / 5 h / Ambient temperature

With osmium(VIII) oxide; tetra-(n-butyl)ammonium iodide; sodium hydride; 4-methylmorpholine N-oxide; In tetrahydrofuran; water; acetone;
DOI:10.1021/jo00040a043

Reference yield:

: 142458-28-4
6β-<(tert-butyldimethylsilyl)oxy>-5α,7α-dimethoxycyclohepta-1,3-diene

: 142482-31-3
1β,5β-bis(benzyloxy)-3β-<(tert-butyldimethylsilyl)oxy>-6α,7α-dihydroxy-2α,4α-dimethoxycycloheptane

Guidance literature:: Multi-step reaction with 4 steps

1: 76 percent / O₂, tetraphenylporphin / CH₂Cl₂ / 3 h / Irradiation

2: 83 mg / thiourea / methanol / 36 h / Ambient temperature

3: 91.6 percent / NaH, Bu₄NI / tetrahydrofuran / 12 h / Ambient temperature

4: 87 percent / OsO₄, N-methylmorpholine N-oxide / acetone; H₂O; tetrahydrofuran / 5 h / Ambient temperature

With osmium(VIII) oxide; oxygen; 5,15,10,20-tetraphenylporphyrin; tetra-(n-butyl)ammonium iodide; sodium hydride; 4-methylmorpholine N-oxide; thiourea; In tetrahydrofuran; methanol; dichloromethane; water; acetone;
DOI:10.1021/jo00040a043