jesaconitine

Base Information

• Chemical Name: jesaconitine
• CAS No.: 16298-90-1
• Molecular Formula: C35H49 N O12
• Molecular Weight: 675.774
• Mol file: 16298-90-1.mol

Synonyms:Jesaconitine(6CI,8CI); 2H-12,3,6a-Ethanylylidene-7,9-methanonaphth[2,3-b]azocine,aconitane-3,8,13,14,15-pentol deriv.; Diesaconitine

Chemical Property of jesaconitine

Chemical Property:

• Vapor Pressure: 1.66E-23mmHg at 25°C
• Boiling Point: 748.1°C at 760 mmHg
• Flash Point: 406.2°C
• PSA: 162.68000
• Density: 1.37g/cm³
• LogP: 0.59460

Purity/Quality:

97% ^*data from raw suppliers

JESACONITINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: An Aconitine (A189875) analog. Aconitine alkaloid pharmacokinetic analgesic. A highly poisonous, neurotoxic alkaloid.

Technology Process of jesaconitine

There total 2 articles about jesaconitine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

acetic acid (64-19-7,77671-22-8) + secojesaconitine (119212-27-0) → Jesaconitine (16298-90-1)

Guidance literature:

Reference yield:

→ Jesaconitine (16298-90-1)

Guidance literature:

Reference yield: 92.5%

acetic anhydride (108-24-7) + Jesaconitine (16298-90-1) → 3-O-Acetyljesaconitine (119212-25-8)

Guidance literature:

With pyridine; for 2h; Ambient temperature;

DOI:10.1248/cpb.39.379

upstream raw materials:

acetic acid

secojesaconitine

Downstream raw materials:

8-O-Methyl-14-anisoylaconine

8-O-Ethyl-14-anisoylaconine

8-O-Linoleoyl-14-anisoylaconine

3-O-Acetyljesaconitine