1-Benzoyl-5-methoxy-2-methylindole-3-acetic acid

Base Information

• Chemical Name: 1-Benzoyl-5-methoxy-2-methylindole-3-acetic acid
• CAS No.: 1601-19-0
• Molecular Formula: C19H17 N O4
• Molecular Weight: 323.348
• DSSTox Substance ID: DTXSID40400323
• Nikkaji Number: J1.634.843K
• Wikidata: Q82203236
• ChEMBL ID: CHEMBL1256943
• Mol file: 1601-19-0.mol

Synonyms:1-Benzoyl-5-methoxy-2-methylindole-3-acetic acid;1601-19-0;2-(1-benzoyl-5-methoxy-2-methylindol-3-yl)acetic acid;HMS3260E22;NCGC00015138-01;Lopac-B-1183;Lopac0_000110;SCHEMBL1082631;CHEMBL1256943;DTXSID40400323;HHVVFSZNIUHMEJ-UHFFFAOYSA-N;Tox21_500110;CCG-204205;LP00110;SDCCGSBI-0050098.P002;NCGC00015138-02;NCGC00015138-03;NCGC00015138-04;NCGC00093607-01;NCGC00093607-02;NCGC00260795-01;PD015439;EU-0100110;FT-0720797;B 1183;SR-01000075704;SR-01000075704-1;(1-Benzoyl-2-methyl-5-methoxy-3-indolyl)acetic acid;1-Benzoyl-2-methyl-5-methoxy-1H-indole-3-acetic acid;(1-benzoyl-5-methoxy-2-methyl-1H-indol-3-yl)acetic acid

Chemical Property of 1-Benzoyl-5-methoxy-2-methylindole-3-acetic acid

Chemical Property:

• XLogP3: 3.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 323.11575802
• Heavy Atom Count: 24
• Complexity: 474

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C2=C(N1C(=O)C3=CC=CC=C3)C=CC(=C2)OC)CC(=O)O

Technology Process of 1-Benzoyl-5-methoxy-2-methylindole-3-acetic acid

There total 8 articles about 1-Benzoyl-5-methoxy-2-methylindole-3-acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.2%

N1-benzoyl-N1-(4-methoxyphenyl)hydrazine hydrochloride (19369-69-8) + levulinic acid (123-76-2) → 1-benzoyl-5-methoxy-2-methylindole-3-acetic acid (1601-19-0)

Guidance literature:

In acetic acid; at 80 ℃; for 3h;

DOI:10.1016/S0968-0896(00)00292-3

Reference yield: 44.0%

[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid (53-86-1) → 1-benzoyl-5-methoxy-2-methylindole-3-acetic acid (1601-19-0)

Guidance literature:

With hydrogen; triethylamine; palladium on activated charcoal; In methanol; at 20 ℃; for 25h;

DOI:10.1016/S0040-4039(02)01622-2 DOI:10.1016/j.tet.2006.05.025

Reference yield:

methyl (5-methoxy-2-methyl-1H-indol-3-yl)acetate (7588-36-5) → 1-benzoyl-5-methoxy-2-methylindole-3-acetic acid (1601-19-0) + (5-methoxy-2-methyl-1H-indol-3-yl)acetic acid benzyl ester (3285-40-3)

Guidance literature:

With sodium; In benzyl alcohol;

upstream raw materials:

N₁-benzoyl-N₁-(4-methoxyphenyl)hydrazine hydrochloride

levulinic acid

[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid

acetaldehyde N₁-benzoyl-N₁-(4-methoxyphenyl)hydrazone

Downstream raw materials:

(1-benzoyl-5-hydroxy-2-methyl-1H-indol-3-yl)acetic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1601-19-0 1H-Indole-3-aceticacid, 1-benzoyl-5-methoxy-2-methyl-

Send

Send

Metric Ton KG G Pound L ML

Send

Send