Methyl 5-amino-6-iodopicolinate

Base Information

Chemical Name:Methyl 5-amino-6-iodopicolinate
CAS No.:872355-60-7
Molecular Formula:C₇H₇IN₂O₂
Molecular Weight:278.049
Hs Code.:
DSSTox Substance ID:DTXSID50704844
Wikidata:Q82637421
Mol file:872355-60-7.mol

Synonyms:METHYL 5-AMINO-6-IODOPICOLINATE;872355-60-7;methyl 5-amino-6-iodopyridine-2-carboxylate;Methyl5-amino-6-iodopyridine-2-carboxylate;SCHEMBL3112986;DTXSID50704844;XYAWLFXZOHDXKP-UHFFFAOYSA-N;XJB35560;MFCD11977097;METHYL5-AMINO-6-IODOPICOLINATE;AS-65547;BP-11825;CS-0080246;EN300-93619;A922511

Suppliers and Price of Methyl 5-amino-6-iodopicolinate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
Methyl 5-amino-6-iodopyridine-2-carboxylate
5g
$ 2700.00

Matrix Scientific
Methyl 5-amino-6-iodopyridine-2-carboxylate
1g
$ 900.00

Frontier Specialty Chemicals
Methyl5-amino-6-iodopyridine-2-carboxylate
1g
$ 360.00

Crysdot
Methyl5-amino-6-iodopicolinate 97%
1g
$ 735.00

Chemcia Scientific
5-Amino-6-iodo-pyridine-2-carboxylicacidmethylester ＞95%
0.5 G
$ 250.00

American Custom Chemicals Corporation
METHYL-5-AMINO-6-IODOPYRIDINE-2-CARBOXYLATE 95.00%
5MG
$ 497.27

AK Scientific
Methyl5-amino-6-iodopyridine-2-carboxylate
250mg
$ 790.00

Total 7 raw suppliers

Chemical Property of Methyl 5-amino-6-iodopicolinate

Chemical Property:

XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:277.95523
Heavy Atom Count:12
Complexity:177

Purity/Quality:

97% ^*data from raw suppliers

Methyl 5-amino-6-iodopyridine-2-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)C1=NC(=C(C=C1)N)I

Technology Process of Methyl 5-amino-6-iodopicolinate

There total 3 articles about Methyl 5-amino-6-iodopicolinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 67515-76-8
methyl 5-amino-2-pyridinecarboxylate

: 872355-60-7
methyl 5-amino-6-iodopyridine-2-carboxylate

Guidance literature:: With sodium periodate; iodine; In N,N-dimethyl-formamide; at 60 ℃;
DOI:10.1016/j.bmcl.2009.08.005

Reference yield:

: 24242-20-4,114849-40-0
5-amino-pyridine-2-carboxylic acid

: 872355-60-7
methyl 5-amino-6-iodopyridine-2-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride / 30 h / 0 °C / Heating / reflux

2: sodium periodate; iodine / N,N-dimethyl-formamide / 24 h / 60 °C

With sodium periodate; thionyl chloride; iodine; In N,N-dimethyl-formamide;

Reference yield:

: 55338-73-3
5-amino-2-cyanopyridine

: 872355-60-7
methyl 5-amino-6-iodopyridine-2-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1.1: sulfuric acid / 2 h / 90 °C

1.2: 2 h / 100 °C

2.1: thionyl chloride / 30 h / 0 °C / Heating / reflux

3.1: sodium periodate; iodine / N,N-dimethyl-formamide / 24 h / 60 °C

With sodium periodate; thionyl chloride; sulfuric acid; iodine; In N,N-dimethyl-formamide;