N,N-diphenyl-4'-(1-phenyl-1H-benzo[d]imidazol-2-yl)-[1,1'-biphenyl]-4-amine

Base Information

• Chemical Name: N,N-diphenyl-4'-(1-phenyl-1H-benzo[d]imidazol-2-yl)-[1,1'-biphenyl]-4-amine
• CAS No.: 1259883-01-6
• Molecular Formula: C₃₇H₂₇N₃
• Molecular Weight: 513.641
• Mol file: 1259883-01-6.mol

Synonyms:N,N-diphenyl-4'-(1-phenyl-1H-benzo[d]imidazol-2-yl)-[1,1'-biphenyl]-4-amine

Chemical Property of N,N-diphenyl-4'-(1-phenyl-1H-benzo[d]imidazol-2-yl)-[1,1'-biphenyl]-4-amine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N-diphenyl-4'-(1-phenyl-1H-benzo[d]imidazol-2-yl)-[1,1'-biphenyl]-4-amine

There total 9 articles about N,N-diphenyl-4'-(1-phenyl-1H-benzo[d]imidazol-2-yl)-[1,1'-biphenyl]-4-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

2-(4-bromophenyl)-1-phenyl-1H-benzimidazole (2620-76-0) + 4-(diphenylamino)phenyl boronic acid (201802-67-7) → N,N-diphenyl-4'-(1-phenyl-1H-benzo[d]imidazol-2-yl)-[1,1'-biphenyl]-4-amine (1259883-01-6)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In tetrahydrofuran; methanol; water; for 24h; Inert atmosphere; Reflux;

DOI:10.1016/j.orgel.2013.06.022

Reference yield: 68.0%

1-phenyl-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-phenyl]-1H-benzo[d]imidazole (1146340-38-6) + 4-N,N-diphenylamino-1-bromobenzene (36809-26-4) → N,N-diphenyl-4'-(1-phenyl-1H-benzo[d]imidazol-2-yl)-[1,1'-biphenyl]-4-amine (1259883-01-6)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; tetraethylammonium hydroxide; In water; toluene; for 18h; Reflux;

DOI:10.1016/j.dyepig.2013.11.023

Reference yield:

4-chlorobenzoyl chloride (586-75-4) → N,N-diphenyl-4'-(1-phenyl-1H-benzo[d]imidazol-2-yl)-[1,1'-biphenyl]-4-amine (1259883-01-6)

Guidance literature:

Multi-step reaction with 3 steps

1: triethylamine / dichloromethane / 20 °C

2: trichlorophosphate / 1,4-dioxane / 100 °C

3: potassium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,4-dioxane; water / 100 °C / Inert atmosphere

With potassium carbonate; triethylamine; trichlorophosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; dichloromethane; water;

upstream raw materials:

4-chlorobenzoyl chloride

4-N,N-diphenylamino-1-bromobenzene

N-phenyl-1,2-benzenediamine

2-(4-bromophenyl)-1-phenyl-1H-benzimidazole