(1R)-2-phenyl-1-pyridin-2-ylethanamine

Base Information

Chemical Name:(1R)-2-phenyl-1-pyridin-2-ylethanamine
CAS No.:138175-27-6
Molecular Formula:C₁₃H₁₄N₂
Molecular Weight:198.268
Hs Code.:
DSSTox Substance ID:DTXSID901260377
Nikkaji Number:J437.147J

Synonyms:138175-27-6;DTXSID901260377;(alphaR)-alpha-(Phenylmethyl)-2-pyridinemethanamine

Suppliers and Price of (1R)-2-phenyl-1-pyridin-2-ylethanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of (1R)-2-phenyl-1-pyridin-2-ylethanamine

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:198.115698455
Heavy Atom Count:15
Complexity:175

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)CC(C2=CC=CC=N2)N
Isomeric SMILES:C1=CC=C(C=C1)C[C@H](C2=CC=CC=N2)N

Technology Process of (1R)-2-phenyl-1-pyridin-2-ylethanamine

There total 3 articles about (1R)-2-phenyl-1-pyridin-2-ylethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3731-51-9
2-(Aminomethyl)pyridine

: 138175-27-6
(R)-2-Phenyl-1-pyridin-2-yl-ethylamine

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / BF₃*Et₃O / benzene / 2.5 h

2: 1.) n-BuLi / 1.) hexane, THF, -78 deg C, 3 h, 2.) hexane , THF, -78 deg C

3: NH₂OH*HOAc / ethanol / 24 h / Heating

With n-butyllithium; boron trifluoride diethyl etherate; hydroxylamine acetate; In ethanol; benzene;

Reference yield:

: 323584-20-9
(1S,2S,5S)-2,6,6-Trimethyl-3-[(Z)-pyridin-2-ylmethylimino]-bicyclo[3.1.1]heptan-2-ol

: 138175-27-6
(R)-2-Phenyl-1-pyridin-2-yl-ethylamine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) n-BuLi / 1.) hexane, THF, -78 deg C, 3 h, 2.) hexane , THF, -78 deg C

2: NH₂OH*HOAc / ethanol / 24 h / Heating

With n-butyllithium; hydroxylamine acetate; In ethanol;