1-[4-methoxy-3-(phenylmethoxy)phenyl]-2-(3,4,5-trimethoxyphenyl)-ethanone

Base Information

• Chemical Name: 1-[4-methoxy-3-(phenylmethoxy)phenyl]-2-(3,4,5-trimethoxyphenyl)-ethanone
• CAS No.: 56766-92-8
• Molecular Formula: C₂₅H₂₆O₆
• Molecular Weight: 422.478
• Mol file: 56766-92-8.mol

Synonyms:1-[4-methoxy-3-(phenylmethoxy)phenyl]-2-(3,4,5-trimethoxyphenyl)-ethanone

Chemical Property of 1-[4-methoxy-3-(phenylmethoxy)phenyl]-2-(3,4,5-trimethoxyphenyl)-ethanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-[4-methoxy-3-(phenylmethoxy)phenyl]-2-(3,4,5-trimethoxyphenyl)-ethanone

There total 8 articles about 1-[4-methoxy-3-(phenylmethoxy)phenyl]-2-(3,4,5-trimethoxyphenyl)-ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

2-hydroxy-2-(3-benzyloxy-4'-methoxyphenyl)-3-(3',4',5'-trimethoxyphenyl)-propanoic acid (330468-45-6) → 1-[4-methoxy-3-(phenylmethoxy)phenyl]-2-(3,4,5-trimethoxyphenyl)-ethanone (56766-92-8)

Guidance literature:

With sodium periodate; In water; acetic acid; acetone; at 25 ℃;

Reference yield:

2-(3-benzyloxy-4-methoxy-phenyl)-2-(3,4,5-trimethoxy-benzyl)-[1,3]dithiane (932033-74-4) → 1-[4-methoxy-3-(phenylmethoxy)phenyl]-2-(3,4,5-trimethoxyphenyl)-ethanone (56766-92-8)

Guidance literature:

With mercury dichloride; mercury(II) oxide; In water; acetonitrile; at 20 ℃; for 16h;

DOI:10.1016/j.bmcl.2006.11.023

Reference yield:

4-methyl-N′-(3,4,5-trimethoxybenzylidene)-benzenesulfonohydrazide (188493-61-0) + 3-benzyloxy-4-methoxybenzaldehyde (6346-05-0) → 1-[4-methoxy-3-(phenylmethoxy)phenyl]-2-(3,4,5-trimethoxyphenyl)-ethanone (56766-92-8)

Guidance literature:

With sodium hydroxide; In ethanol; at 55 ℃; for 48h; Darkness;

DOI:10.1039/c5md00028a

upstream raw materials:

2-hydroxy-2-(3-benzyloxy-4'-methoxyphenyl)-3-(3',4',5'-trimethoxyphenyl)-propanoic acid

2-(3-benzyloxy-4-methoxy-phenyl)-2-(3,4,5-trimethoxy-benzyl)-[1,3]dithiane

2-(3-benzyloxy-4-methoxy-phenyl)-[1,3]dithiane

3,4,5-trimethoxybenzyl bromide

Downstream raw materials:

1-oxo-1-(3''-hydroxy-4''-methoxyphenyl)-2-(3',4'.5'-trimethoxyphenyl)ethane

5-(3-benzyloxy-4-methoxy-phenyl)-4-(3,4,5-trimethoxy-phenyl)-isoxazole

5-[1-hydroxy-2-(3,4,5-trimethoxyphenyl)ethyl]-2-methoxyphenol

1-(3-benzyloxy-4-methoxy-phenyl)-3-dimethylamino-2-(3,4,5-trimethoxy-phenyl)-propenone