(R)-methyl 2-(hydroxy(4-(trifluoromethyl)phenyl)methyl)acrylate

Base Information

• Chemical Name: (R)-methyl 2-(hydroxy(4-(trifluoromethyl)phenyl)methyl)acrylate
• CAS No.: 1199270-26-2
• Molecular Formula: C₁₂H₁₁F₃O₃
• Molecular Weight: 260.213
• Mol file: 1199270-26-2.mol

Synonyms:(R)-methyl 2-(hydroxy(4-(trifluoromethyl)phenyl)methyl)acrylate

Chemical Property of (R)-methyl 2-(hydroxy(4-(trifluoromethyl)phenyl)methyl)acrylate

Chemical Property:

Purity/Quality:

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Technology Process of (R)-methyl 2-(hydroxy(4-(trifluoromethyl)phenyl)methyl)acrylate

There total 1 articles about (R)-methyl 2-(hydroxy(4-(trifluoromethyl)phenyl)methyl)acrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-Trifluoromethylbenzaldehyde (455-19-6) + acrylic acid methyl ester (292638-85-8,9003-21-8,96-33-3) → (S)-methyl 2-(hydroxy(4-(trifluoromethyl)phenyl)methyl)acrylate + (R)-methyl 2-(hydroxy(4-(trifluoromethyl)phenyl)methyl)acrylate (1199270-26-2)

Guidance literature:

With (S)-1-(1-(diphenylphosphino)-3-methylbutan-2-yl)-3-phenylthiourea; In tetrahydrofuran; at 25 ℃; enantioselective reaction; Inert atmosphere;

DOI:10.1016/j.tetasy.2009.07.047

upstream raw materials:

4-Trifluoromethylbenzaldehyde

acrylic acid methyl ester