ethyl 2-mercaptodihydrocinnamate

Base Information

• Chemical Name: ethyl 2-mercaptodihydrocinnamate
• CAS No.: 81536-21-2
• Molecular Formula: C₁₁H₁₄O₂S
• Molecular Weight: 210.297
• Mol file: 81536-21-2.mol

Synonyms:ethyl 2-mercaptodihydrocinnamate

Chemical Property of ethyl 2-mercaptodihydrocinnamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ethyl 2-mercaptodihydrocinnamate

There total 1 articles about ethyl 2-mercaptodihydrocinnamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

triethyl orthoacrylate (42216-96-6) + thiophenol (108-98-5) → ethyl 2-mercaptodihydrocinnamate (81536-21-2)

Guidance literature:

With Trimethylacetic acid; In various solvent(s); for 20h; Heating;

DOI:10.1021/jo00134a022

Reference yield:

ethyl 2-mercaptodihydrocinnamate (81536-21-2) → 2H-thiochromen-2-one (1075-14-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) diphenyl ether, 2.) p-toluenesulfonic acid / 1.) reflux, 24 h, 2.) reflux, 18 h

2: 44 percent / diphenyl ether / 10percent Pd/C / 26 h / Heating

With diphenylether; toluene-4-sulfonic acid; palladium on activated charcoal;

DOI:10.1021/jo00134a022

Reference yield:

ethyl 2-mercaptodihydrocinnamate (81536-21-2) → Dihydro-3,4 thio-1 coumarine (5962-02-7)

Guidance literature:

With diphenylether; toluene-4-sulfonic acid; Yield given. Multistep reaction; 1.) reflux, 24 h, 2.) reflux, 18 h;

DOI:10.1021/jo00134a022

upstream raw materials:

triethyl orthoacrylate

thiophenol

Downstream raw materials:

Dihydro-3,4 thio-1 coumarine

2H-thiochromen-2-one