Quifenadine

Base Information

Chemical Name:Quifenadine
CAS No.:10447-39-9
Molecular Formula:C20H23NO
Molecular Weight:293.409
Hs Code.:2933990090
UNII:W9A18RJ49B
DSSTox Substance ID:DTXSID6046187
Nikkaji Number:J10.456F
Wikipedia:Quifenadine
Wikidata:Q4497981
NCI Thesaurus Code:C81147
Metabolomics Workbench ID:154498
ChEMBL ID:CHEMBL1187694
Mol file:10447-39-9.mol

Synonyms:Fenatin;Fencarol;Phencarol;quifenadine;quifenadine hydrobromide, (+-)-isomer;quifenadine hydrochloride;quinuclidinyl-3-diphenylcarbinol

Suppliers and Price of Quifenadine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Quifenadine
10mg
$ 460.00

TRC
Quifenadine
100mg
$ 1135.00

TRC
Quifenadine
10mg
$ 145.00

Medical Isotopes, Inc.
Quifenadine
100 mg
$ 1600.00

American Custom Chemicals Corporation
QUIFENADINE 95.00%
500MG
$ 345.45

Total 60 raw suppliers

Chemical Property of Quifenadine

Chemical Property:

Vapor Pressure:3.65E-08mmHg at 25°C
Melting Point:239℃
Refractive Index:1.64
Boiling Point:430.173 °C at 760 mmHg
PKA:13.26±0.29(Predicted)
Flash Point:208.033 °C
PSA：23.47000
Density:1.178 g/cm³
LogP:4.00420
Storage Temp.:Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility.:Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly)
XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:293.177964357
Heavy Atom Count:22
Complexity:344

Purity/Quality:: Quifenadine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN2CCC1C(C2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O
Uses Quifenadine is used in the biological studies of azoniabicyclooctanes as muscarinic acetylcholine receptor antagonists.

Technology Process of Quifenadine

There total 2 articles about Quifenadine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 29.3%

: 38206-86-9
methyl quinuclidine-3-carboxylate

: 100-58-3
phenylmagnesium bromide

: 10447-39-9
(1-aza-bicyclo[2.2.2]oct-3-yl)-diphenyl-methanol

Guidance literature:: methyl quinuclidine-3-carboxylate; phenylmagnesium bromide; In tetrahydrofuran; diethyl ether; at 0 - 60 ℃; Inert atmosphere;

With ammonium chloride; In tetrahydrofuran; diethyl ether; water; at 0 ℃;
DOI:10.1021/jm801601v