(2R,4S,5S)-N-isobutyl-5-(benzyloxycarbonyl)amino-2-ethyl-4-hydroxy-7-methyloctanamide

Base Information

Chemical Name:(2R,4S,5S)-N-isobutyl-5-(benzyloxycarbonyl)amino-2-ethyl-4-hydroxy-7-methyloctanamide
CAS No.:130900-30-0
Molecular Formula:C₂₃H₃₈N₂O₄
Molecular Weight:406.566
Hs Code.:

Synonyms:(2R,4S,5S)-N-isobutyl-5-(benzyloxycarbonyl)amino-2-ethyl-4-hydroxy-7-methyloctanamide

Suppliers and Price of (2R,4S,5S)-N-isobutyl-5-(benzyloxycarbonyl)amino-2-ethyl-4-hydroxy-7-methyloctanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (2R,4S,5S)-N-isobutyl-5-(benzyloxycarbonyl)amino-2-ethyl-4-hydroxy-7-methyloctanamide

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

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Hazard Codes:

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Technology Process of (2R,4S,5S)-N-isobutyl-5-(benzyloxycarbonyl)amino-2-ethyl-4-hydroxy-7-methyloctanamide

There total 4 articles about (2R,4S,5S)-N-isobutyl-5-(benzyloxycarbonyl)amino-2-ethyl-4-hydroxy-7-methyloctanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.5%

: 78-81-9
isobutylamine

: 141713-84-0
(2R,4S,5S)-5-(benzyloxycarbonyl)amino-2-ethyl-4-hydroxy-7-methyloctanoic acid γ-lactone

: 130900-30-0
(2R,4S,5S)-N-isobutyl-5-(benzyloxycarbonyl)amino-2-ethyl-4-hydroxy-7-methyloctanamide

Guidance literature:: at 100 ℃; for 6h;
DOI:10.1248/cpb.40.364

Reference yield: 77.0%

: 129831-80-7,129831-81-8
(2RS,4S,5S)-N-Isobutyl-5-amino-2-ethyl-4-hydroxy-7-methyloctanamide

: 42116-21-2
2-benzyloxycarbonylsulfanyl-4,6-dimethyl-pyrimidine

: 130981-01-0
(2R,4S,5S)-N-Isobutyl-5-benzyloxycarbonylamino-2-ethyl-4-hydroxy-7-methyloctanamide

: 130900-30-0
(2R,4S,5S)-N-isobutyl-5-(benzyloxycarbonyl)amino-2-ethyl-4-hydroxy-7-methyloctanamide

Guidance literature:: With triethylamine; In 1,4-dioxane; water; at 30 ℃;
DOI:10.1246/bcsj.63.2224

Reference yield:

: (4S,5S)-5-(2-Ethoxycarbonyl-butyl)-4-isobutyl-2,2-dimethyl-oxazolidine-3-carboxylic acid benzyl ester

: 130900-30-0
(2R,4S,5S)-N-isobutyl-5-(benzyloxycarbonyl)amino-2-ethyl-4-hydroxy-7-methyloctanamide

Guidance literature:: Multi-step reaction with 2 steps

1: p-toluenesulfonic acid / methanol / 3 h / Ambient temperature

2: 88.5 percent / 6 h / 100 °C

With toluene-4-sulfonic acid; In methanol;
DOI:10.1248/cpb.40.364