<4'-O-(p-Nitrobenzoyl)-2',3'-dideoxy-α-D-glycero-pent-2'-enopyranosyl>-N⁴-benzoylcytosine

Base Information

• Chemical Name: <4'-O-(p-Nitrobenzoyl)-2',3'-dideoxy-α-D-glycero-pent-2'-enopyranosyl>-N⁴-benzoylcytosine
• CAS No.: 162934-39-6
• Molecular Formula: C₂₃H₁₈N₄O₇
• Molecular Weight: 462.419
• Mol file: 162934-39-6.mol

Synonyms:<4'-O-(p-Nitrobenzoyl)-2',3'-dideoxy-α-D-glycero-pent-2'-enopyranosyl>-N⁴-benzoylcytosine

Chemical Property of <4'-O-(p-Nitrobenzoyl)-2',3'-dideoxy-α-D-glycero-pent-2'-enopyranosyl>-N⁴-benzoylcytosine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of <4'-O-(p-Nitrobenzoyl)-2',3'-dideoxy-α-D-glycero-pent-2'-enopyranosyl>-N⁴-benzoylcytosine

There total 5 articles about <4'-O-(p-Nitrobenzoyl)-2',3'-dideoxy-α-D-glycero-pent-2'-enopyranosyl>-N⁴-benzoylcytosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

D-xylal (496-62-8) → <4'-O-(p-Nitrobenzoyl)-2',3'-dideoxy-α-D-glycero-pent-2'-enopyranosyl>-N4-benzoylcytosine (162934-39-6)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / 0 °C

2: dimethylformamide / 0.25 h / Heating

With pyridine; In N,N-dimethyl-formamide;

DOI:10.1021/jo00129a035

Reference yield:

3,4-di-O-acetyl-D-xylal (3152-43-0) → <4'-O-(p-Nitrobenzoyl)-2',3'-dideoxy-α-D-glycero-pent-2'-enopyranosyl>-N4-benzoylcytosine (162934-39-6)

Guidance literature:

Multi-step reaction with 3 steps

1: NaOMe / methanol

2: pyridine / 0 °C

3: dimethylformamide / 0.25 h / Heating

With pyridine; sodium methylate; In methanol; N,N-dimethyl-formamide;

DOI:10.1021/jo00129a035

Reference yield:

N-(2-Trimethylsilanyloxy-pyrimidin-4-yl)-benzamide (85743-99-3) + 3,4-Bis-O-(p-nitrobenzoyl)-D-xylal (162934-25-0) → <4'-O-(p-Nitrobenzoyl)-2',3'-dideoxy-β-D-glycero-pent-2'-enopyranosyl>-N4-benzoylcytosine (162934-38-5) + <4'-O-(p-Nitrobenzoyl)-2',3'-dideoxy-α-D-glycero-pent-2'-enopyranosyl>-N4-benzoylcytosine (162934-39-6) + 4-Nitro-benzoic acid (S)-4-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-3,4-dihydro-2H-pyran-3-yl ester

Guidance literature:

In N,N-dimethyl-formamide; for 0.25h; Yield given. Yields of byproduct given; Heating;

DOI:10.1021/jo00129a035

upstream raw materials:

4-N-benzoylcytosine

3,4-Bis-O-(p-nitrobenzoyl)-D-xylal

N-(2-((1-trimethylsilyl)oxy)pyrimidin-4-yl)benzamide

N-(2-Trimethylsilanyloxy-pyrimidin-4-yl)-benzamide

Downstream raw materials:

2',3'-Dideoxy-α-D-glycero-pent-2'-enopyranosyl-N⁴-benzoylcytosine