3152-43-0

Basic information

• Product Name: 3,4-DI-O-ACETYL-D-XYLAL,
• Synonyms: (3R,4R)-3,4-dihydro-2H-pyran-3,4-diyl diacetate;Diacetyl-D-xylal;Di-O-acetyl-D-xylal;D-Xylal diacetate;1,5-Anhydro-2-deoxy-D-threo-pent-1-enitol 3,4-diacetate
• CAS NO: 3152-43-0
• Molecular Formula: C₉H₁₂O₅
• Molecular Weight: 200.189
• Mol File: 3152-43-0.mol
• Article Data: 34

Chemical Properties

• Melting Point: 40-42 °C(Solv: ethyl acetate (141-78-6))
• Boiling Point: 266.2°Cat760mmHg
• Flash Point: 112.8°C
• Appearance: /
• Density: 1.2g/cm³
• Vapor Pressure: 0.00878mmHg at 25°C
• Refractive Index: 1.476
• CAS DataBase Reference: 3,4-DI-O-ACETYL-D-XYLAL,(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-DI-O-ACETYL-D-XYLAL,(3152-43-0)
• EPA Substance Registry System: 3,4-DI-O-ACETYL-D-XYLAL,(3152-43-0)

Safety Data

• Safety Statements: S24/25:Avoid contact with skin and eyes.
• Hazardous Substances Data: 3152-43-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H12O5/c1-6(10)13-8-3-4-12-5-9(8)14-7(2)11/h3-4,8-9H,5H2,1-2H3/t8-,9-/m1/s1

Upstream product

• 107-13-1 acrylonitrile 
• 4258-01-9 1,3,4-tri-O-acetyl-2-deoxy-β-D-erythro-pentopyranose 
• 64-19-7 acetic acid 
• 127-09-3 sodium acetate 
• 3068-31-3 1-bromo-2,3,4-tri-O-acetyl-α-D-xylopyranose 
• 108-24-7 acetic anhydride 
• 10343-54-1 2,3,4-tri-O-acetyl-α-D-xylopyranosyl chloride 
• 496-62-8 D-xylal 
• 58-86-6 D-xylose 
• 62446-93-9 1,2,3,4-tetra-O-acetyl-D-xylopyranose 
• 3056-11-9 D-xylosyl bromide 
• 10323-20-3 D-Arabinose 
• 113889-50-2 (3S,4R,5R)-2-bromotetrahydro-2H-pyran-3,4,5-triyl triacetate 
• 19186-37-9 1,2,3,4-tetra-O-acetyl-α-D-arabinopyranose 

Downstream Products

• 162934-25-0 3,4-Bis-O-(p-nitrobenzoyl)-D-xylal 
• 162934-40-9 2',3'-Dideoxy-β-D-glycero-pent-2'-enopyranosyl-N⁴-benzoylcytosine 
• 162934-41-0 2',3'-Dideoxy-α-D-glycero-pent-2'-enopyranosyl-N⁴-benzoylcytosine 
• 162934-32-9 (2',3'-Dideoxy-β-D-glycero-pent-2'-enopyranosyl)-N⁶-benzoyladenine 
• 162934-33-0 (2',3'-Dideoxy-α-D-glycero-pent-2'-enopyranosyl)-N⁶-benzoyladenine 
• 162934-34-1 <4'-O-(p-Nitrobenzoyl)-2',3'-dideoxy-β-D-glycero-pent-2'-enopyranosyl>-6-chloropurine 
• 162934-35-2 <4'-O-(p-Nitrobenzoyl)-2',3'-dideoxy-α-D-glycero-pent-2'-enopyranosyl>-6-chloropurine 
• 162934-38-5 <4'-O-(p-Nitrobenzoyl)-2',3'-dideoxy-β-D-glycero-pent-2'-enopyranosyl>-N⁴-benzoylcytosine 
• 162934-39-6 <4'-O-(p-Nitrobenzoyl)-2',3'-dideoxy-α-D-glycero-pent-2'-enopyranosyl>-N⁴-benzoylcytosine 
• 169514-08-3 <4'-O-(p-Nitrobenzoyl)-2',3'-dideoxy-α-D-glycero-pent-2'-enopyranosyl>uracil 
• 162934-28-3 (2',3'-Dideoxy-β-D-glycero-pent-2'-enopyranosyl)-N²-isobutyryl-O⁶-<2-(p-nitrophenyl)ethyl>guanine 

Relevant articles and documents

Sugar-Based Polymers from d-Xylose: Living Cascade Polymerization, Tunable Degradation, and Small Molecule Release

Enyne monomers derived from D-xylose underwent living cascade polymerizations to prepare new polymers with a ring-opened sugar and degradable linkage incorporated into every repeat unit of the backbone. Polymerizations were well-controlled and had living character, which enabled the preparation of high molecular weight polymers with narrow molecular weight dispersity values and a block copolymer. By tuning the type of acid-sensitive linkage (hemi-aminal ether, acetal, or ether functional groups), we could change the degradation profile of the polymer and the identity of the resulting degradation products. For instance, the large difference in degradation rates between hemi-aminal ether and ether-based polymers enabled the sequential degradation of a block copolymer. Furthermore, we exploited the generation of furan-based degradation products, from an acetal-based polymer, to achieve the release of covalently bound reporter molecules upon degradation.

Non-naturally Occurring Regio Isomer of Lysophosphatidylserine Exhibits Potent Agonistic Activity toward G Protein-Coupled Receptors

Lysophosphatidylserine (LysoPS), an endogenous ligand of G protein-coupled receptors, consists of l-serine, glycerol, and fatty acid moieties connected by phosphodiester and ester linkages, respectively. An ester linkage of phosphatidylserine can be hydrolyzed at the 1-position or at the 2-position to give 2-acyl lysophospholipid or 1-acyl lysophospholipid, respectively. 2-Acyl lysophospholipid is in nonenzymatic equilibrium with 1-acyl lysophospholipid in vivo. On the other hand, 3-acyl lysophospholipid is not found, at least in mammals, raising the question of whether the reason for this might be that the 3-acyl isomer lacks the biological activities of the other isomers. Here, to test this idea, we designed and synthesized a series of new 3-acyl lysophospholipids. Structure-activity relationship studies of more than 100 "glycol surrogate"derivatives led to the identification of potent and selective agonists for LysoPS receptors GPR34 and P2Y10. Thus, the non-natural 3-acyl compounds are indeed active and appear to be biologically orthogonal with respect to the physiologically relevant 1-and 2-acyl lysophospholipids.

Preparation method and application of xylose carbon glycoside drug

The invention provides an xylose carbon glycoside drug. A structural formula of the compound is as follows as show in the specification, wherein Ar comprises Ph-, 3-F-Ph- or 3,5-F2-Ph-; and R comprises n-Pr-, PhCH2CH2- or i-Pr-. A preparation method of th