(2R,3R)-1-(4-methoxy-benzenesulfonyl)-2-methyl-3-phenyl-aziridine

Base Information

• Chemical Name: (2R,3R)-1-(4-methoxy-benzenesulfonyl)-2-methyl-3-phenyl-aziridine
• CAS No.: 1085390-04-0
• Molecular Formula: C₁₆H₁₇NO₃S
• Molecular Weight: 303.382
• Mol file: 1085390-04-0.mol

Synonyms:(2R,3R)-1-(4-methoxy-benzenesulfonyl)-2-methyl-3-phenyl-aziridine

Chemical Property of (2R,3R)-1-(4-methoxy-benzenesulfonyl)-2-methyl-3-phenyl-aziridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2R,3R)-1-(4-methoxy-benzenesulfonyl)-2-methyl-3-phenyl-aziridine

There total 1 articles about (2R,3R)-1-(4-methoxy-benzenesulfonyl)-2-methyl-3-phenyl-aziridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-propenylbenzene (873-66-5) + C13H12INO3S (181306-52-5) → (2R,3R)-1-(4-methoxy-benzenesulfonyl)-2-methyl-3-phenyl-aziridine (1085390-04-0) + (2S,3S)-1-(4-Methoxy-benzenesulfonyl)-2-methyl-3-phenyl-aziridine

Guidance literature:

With copper (I) trifluoromethane sulfonate benzene; 2,2'-isopropylidenebis<(4S)-4-tert-butyl-4,5-dihydrooxazole>; 4 A molecular sieve; In acetonitrile; at -25 ℃; for 48h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1016/S0957-4166(97)00496-5

Reference yield: 92.0%

(2R,3R)-1-(4-methoxy-benzenesulfonyl)-2-methyl-3-phenyl-aziridine (1085390-04-0) → (1R,2S)-N-(2-azido-1-methyl-2-phenyl-ethyl)-4-methoxy-benzenesulfonamide (1085390-15-3)

Guidance literature:

With sodium azide; water; In acetonitrile; for 1h; Reflux;

DOI:10.1021/jo8019863

upstream raw materials:

1-propenylbenzene

C₁₃H₁₂INO₃S

Downstream raw materials:

(1R,2S)-N-(2-azido-1-methyl-2-phenyl-ethyl)-4-methoxy-benzenesulfonamide