S-Deoxo-(R)-sparasomycin

Base Information

Chemical Name:S-Deoxo-(R)-sparasomycin
CAS No.:60484-34-6
Molecular Formula:C13H19N3O4S2
Molecular Weight:345.4377
Hs Code.:
NSC Number:250424,212568
ChEMBL ID:CHEMBL115026

Synonyms:NSC212568;S-Deoxo-(R)-sparasomycin;CHEMBL115026;SPARSOMYCIN, S-DEOXO-(R)-;NSC250424;NSC-212568;NSC-250424;61827-17-6;60484-34-6

Suppliers and Price of S-Deoxo-(R)-sparasomycin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of S-Deoxo-(R)-sparasomycin

Chemical Property:

Density:1.376g/cm³
XLogP3:-0.1
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:8
Exact Mass:345.08169844
Heavy Atom Count:22
Complexity:506

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(=O)NC(=O)N1)C=CC(=O)NC(CO)CSCSC
Isomeric SMILES:CC1=C(C(=O)NC(=O)N1)/C=C/C(=O)NC(CO)CSCSC

Technology Process of S-Deoxo-(R)-sparasomycin

There total 8 articles about S-Deoxo-(R)-sparasomycin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 77826-62-1
Methyl 2-<β-(6-Methyl-5-uracilyl)acrylamido>-3-<<(methylthio)methyl>sulfido>propionate

: 60484-34-6
S-Deoxo-(R)-sparsomycin

Guidance literature:: With lithium borohydride; In 1,2-dimethoxyethane; 1.) -78 deg C; 2.) room temp., 2 h;
DOI:10.1021/jo00329a027

Reference yield:

: 626-48-2
6-Methyluracil

: 60484-34-6
S-Deoxo-(R)-sparsomycin

Guidance literature:: Multi-step reaction with 6 steps

1: 73 percent / 5percent aq NaOH / H₂O / 16 h / Ambient temperature

2: 63 percent / K₂S₂O₈, AgNO₃ / H₂O / 1.) 90-100 deg C; 2.) room temp. 16 h

3: 40 percent / dimethylformamide / 96 h / Ambient temperature

4: 90 percent / NaOH / methanol; dioxane; H₂O / 16 h / 40 °C

5: 1.) Triethylamine; 2.) Hydroxybenztriazole, DCC / DMF, room temp., 16 h

6: 63 percent / LiBH₄ / 1,2-dimethoxy-ethane / 1.) -78 deg C; 2.) room temp., 2 h

With sodium hydroxide; dipotassium peroxodisulfate; lithium borohydride; benzotriazol-1-ol; silver nitrate; triethylamine; dicyclohexyl-carbodiimide; In 1,4-dioxane; methanol; 1,2-dimethoxyethane; water; N,N-dimethyl-formamide;
DOI:10.1021/jo00329a027

Reference yield:

: 147-61-5
5-hydroxymethyl-6-methyluracil

: 60484-34-6
S-Deoxo-(R)-sparsomycin

Guidance literature:: Multi-step reaction with 5 steps

1: 63 percent / K₂S₂O₈, AgNO₃ / H₂O / 1.) 90-100 deg C; 2.) room temp. 16 h

2: 40 percent / dimethylformamide / 96 h / Ambient temperature

3: 90 percent / NaOH / methanol; dioxane; H₂O / 16 h / 40 °C

4: 1.) Triethylamine; 2.) Hydroxybenztriazole, DCC / DMF, room temp., 16 h

5: 63 percent / LiBH₄ / 1,2-dimethoxy-ethane / 1.) -78 deg C; 2.) room temp., 2 h

With sodium hydroxide; dipotassium peroxodisulfate; lithium borohydride; benzotriazol-1-ol; silver nitrate; triethylamine; dicyclohexyl-carbodiimide; In 1,4-dioxane; methanol; 1,2-dimethoxyethane; water; N,N-dimethyl-formamide;
DOI:10.1021/jo00329a027