Technology Process of 1,3-O-benzylidene-2.5-O-methylene-D-glycero-D-manno-heptitol
There total 8 articles about 1,3-O-benzylidene-2.5-O-methylene-D-glycero-D-manno-heptitol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen;
palladium 10% on activated carbon;
In
methanol;
for 12h;
under 4137.29 Torr;
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: 1H-imidazole / N,N-dimethyl-formamide / 2 h / 0 °C / Inert atmosphere
2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0 °C
2.2: 0 - 20 °C
3.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 20 h / 20 °C
4.1: sodium hydrogencarbonate; Dess-Martin periodane / 0.25 h / 20 °C
5.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C
5.2: -78 - 20 °C
6.1: AD-mix-β / water; tert-butyl alcohol / 168 h / 0 °C
7.1: hydrogen / palladium 10% on activated carbon / methanol / 12 h / 4137.29 Torr
With
1H-imidazole; n-butyllithium; AD-mix-β; tetrabutyl ammonium fluoride; hydrogen; sodium hydride; sodium hydrogencarbonate; Dess-Martin periodane;
palladium 10% on activated carbon;
In
tetrahydrofuran; methanol; hexane; water; N,N-dimethyl-formamide; mineral oil; tert-butyl alcohol;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C
1.2: -78 - 20 °C
2.1: AD-mix-β / water; tert-butyl alcohol / 168 h / 0 °C
3.1: hydrogen / palladium 10% on activated carbon / methanol / 12 h / 4137.29 Torr
With
n-butyllithium; AD-mix-β; hydrogen;
palladium 10% on activated carbon;
In
tetrahydrofuran; methanol; hexane; water; tert-butyl alcohol;
