55645-87-9

Upstream product

• 1125-88-8 benzaldehyde dimethyl acetal 
• 36566-49-1 (4R,5R,6R,7R)-4,7-bis(hydroxymethyl)-1,3-dioxepane-5,6-diol 
• 23393-22-8 1,3:4,6-di-O-benzylidene-2,5-O-methylene-D-mannitol 
• 28224-73-9 1,3:4,6-di-O-benzylidene-D-mannitol 

Downstream Products

• 1143516-29-3 4,6,7-tri-O-benzyl-2,5-O-methylene-D-glycero-D-manno-heptitol 
• 1143516-30-6 4,6,7-tri-O-benzyl-2,5-O-methylene-D-glycero-D-manno-heptitol-1,3-cyclic sulfate 
• 1143516-36-2 1,4-dideoxy-1,4-[(2S,3S,4R,5R,6R)-4,6,7-tri-O-benzyl-2,5-O-methylene-3-(sulfooxy)heptyl]-(R)-epi-sulfoniumylidine-D-arabinitol inner salt 
• 1143516-35-1 C₅₈H₆₆O₁₅S₂ 
• 1143516-42-0 1,3-O-benzylidene-2.5-O-methylene-D-glycero-D-manno-heptitol 
• 1143516-28-2 4-O-benzyl-1,3-O-benzylidene-2,5-O-methylene-D-glycero-D-manno-heptitol 
• 1143516-32-8 4-O-benzyl-5,7-O-benzylidene-3,6-O-methylene-D-glycero-D-galacto-heptitol 

Relevant academic research and scientific papers

METHODS FOR SYNTHESIZING KOTALANOL AND STEREOISOMERS AND ANALOGUES THEREOF, AND NOVEL COMPOUNDS PRODUCED THEREBY

Compounds having the general formula (I): wherein X is S, Se or NH, and stereoisomers thereof, and de-O-sulfonated analogues of all of the foregoing, but excluding naturally occurring kotalanol and de-O-sulfonated kotalanol, and methods for synthesizing same. The compounds are useful as glycosidase inhibitors, and may be used in the treatment of diabetes. The synthetic compounds may also be used as standards in the calibration or grading of natural or herbal remedies produced from natural sources of glycosidase inhibitors such as kotalanol.