3-cyclopropylmethoxy-5-methyl-1-(pivaloyloxymethyl)cyclohexa-2,5-diene-1-carboxylic acid methyl ester

Base Information

• Chemical Name: 3-cyclopropylmethoxy-5-methyl-1-(pivaloyloxymethyl)cyclohexa-2,5-diene-1-carboxylic acid methyl ester
• CAS No.: 1194258-79-1
• Molecular Formula: C₁₉H₂₈O₅
• Molecular Weight: 336.428
• Mol file: 1194258-79-1.mol

Synonyms:3-cyclopropylmethoxy-5-methyl-1-(pivaloyloxymethyl)cyclohexa-2,5-diene-1-carboxylic acid methyl ester

Chemical Property of 3-cyclopropylmethoxy-5-methyl-1-(pivaloyloxymethyl)cyclohexa-2,5-diene-1-carboxylic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-cyclopropylmethoxy-5-methyl-1-(pivaloyloxymethyl)cyclohexa-2,5-diene-1-carboxylic acid methyl ester

There total 1 articles about 3-cyclopropylmethoxy-5-methyl-1-(pivaloyloxymethyl)cyclohexa-2,5-diene-1-carboxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-cyclopropylmethoxy-5-methyl-1-(pivaloyloxymethyl)cyclohexa-2,5-diene-1-carboxylic acid (1194258-03-1) + methyl iodide (74-88-4) → 3-cyclopropylmethoxy-5-methyl-1-(pivaloyloxymethyl)cyclohexa-2,5-diene-1-carboxylic acid methyl ester (1194258-79-1)

Guidance literature:

With potassium carbonate; In acetone; at 20 ℃; Reflux; Inert atmosphere;

DOI:10.1021/jo901834q

Reference yield: 69.0%

3-cyclopropylmethoxy-5-methyl-1-(pivaloyloxymethyl)cyclohexa-2,5-diene-1-carboxylic acid methyl ester (1194258-79-1) → 3-cyclopropylmethoxy-5-methyl-2,5-cyclohexadiene-1,1-dimethanol (1194258-05-3)

Guidance literature:

3-cyclopropylmethoxy-5-methyl-1-(pivaloyloxymethyl)cyclohexa-2,5-diene-1-carboxylic acid methyl ester; With lithium aluminium tetrahydride; In diethyl ether; at 20 ℃; for 17h; Inert atmosphere; Cooling with acetone-dry ice;

With water; sodium hydroxide; In diethyl ether; at 20 ℃; Inert atmosphere;

DOI:10.1021/jo901834q

upstream raw materials:

3-cyclopropylmethoxy-5-methyl-1-(pivaloyloxymethyl)cyclohexa-2,5-diene-1-carboxylic acid

methyl iodide

Downstream raw materials:

3-cyclopropylmethoxy-5-methyl-2,5-cyclohexadiene-1,1-dimethanol