tert-butyl-2-fluoro-4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenylcarbamate

Base Information

Chemical Name:tert-butyl-2-fluoro-4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenylcarbamate
CAS No.:1160825-88-6
Molecular Formula:C₁₇H₁₇FN₄O₄
Molecular Weight:360.345
Hs Code.:

Synonyms:tert-butyl-2-fluoro-4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenylcarbamate

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Chemical Property of tert-butyl-2-fluoro-4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenylcarbamate

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Technology Process of tert-butyl-2-fluoro-4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenylcarbamate

There total 1 articles about tert-butyl-2-fluoro-4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 32315-10-9
bis(trichloromethyl) carbonate

: 1163720-66-8
4-(4-N-(tert-butoxycarbonyl)amino-3-fluorophenoxy)-2,3-diaminopyridine

: 1160825-88-6
tert-butyl-2-fluoro-4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenylcarbamate

Guidance literature:: With pyridine; In tetrahydrofuran; at 0 - 20 ℃;
DOI:10.1021/jm900242c

Reference yield: 82.0%

: 1160825-88-6
tert-butyl-2-fluoro-4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenylcarbamate

: 884339-99-5
7-(3-fluoro-4-aminophenyloxy)-1H-imidazo[4,5-b]pyridin-2(3H)-one

Guidance literature:: tert-butyl-2-fluoro-4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)phenylcarbamate; With trifluoroacetic acid; at 20 ℃; for 1.5h;

With sodium carbonate; In water; pH=7;
DOI:10.1021/jm900242c