p-methoxybenzyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranoside

Base Information

Chemical Name:p-methoxybenzyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranoside
CAS No.:93417-34-6
Molecular Formula:C₂₈H₂₉NO₁₁
Molecular Weight:555.538
Hs Code.:

Synonyms:p-methoxybenzyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranoside

Suppliers and Price of p-methoxybenzyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of p-methoxybenzyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranoside

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of p-methoxybenzyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranoside

There total 1 articles about p-methoxybenzyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 105-13-5
4-Methoxybenzyl alcohol

: 10028-45-2
3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl bromide

: 93417-34-6
p-methoxybenzyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranoside

Guidance literature:: With 2,4,6-trimethyl-pyridine; silver trifluoromethanesulfonate; In dichloromethane; for 2h; -30 deg C -> room temperature;

Reference yield: 96.0%

: 93417-34-6
p-methoxybenzyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranoside

: 93417-35-7
p-methoxybenzyl 2-deoxy-2-phthalimido-β-D-glucopyranoside

Guidance literature:: With sodium methylate; In methanol;

Reference yield:

: 93417-34-6
p-methoxybenzyl 3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranoside

: Acetic acid (2R,3S,4R,5R,6S)-3-acetoxy-2-acetoxymethyl-5-amino-6-[(2R,3S,4R,5R,6R)-5-amino-4,6-bis-(4-methoxy-benzyloxy)-2-(4-methoxy-benzyloxymethyl)-tetrahydro-pyran-3-yloxy]-tetrahydro-pyran-4-yl ester

Guidance literature:: Multi-step reaction with 6 steps

1: NaOMe / methanol; CH₂Cl₂ / 2 h / 20 °C

2: 2.52 g / (+/-)-camphor-10-sulfonic acid / dimethylformamide / 4 h / 20 - 30 °C

3: 51 percent / NaH; tetrabutylammonium iodide / dimethylformamide / 20 °C

4: 100 percent / sodium cyanoborohydride; MS₃A; trifluoroacetic acid / dimethylformamide / 48 h / 20 °C

5: 91 percent / MS₄A; trimethylsilyl triflate / CH₂Cl₂ / 1 h / -20 °C

6: hydrazine monohydrate / ethanol; H₂O / 5 h / 90 °C

With trimethylsilyl trifluoromethanesulfonate; camphor-10-sulfonic acid; sodium methylate; tetra-(n-butyl)ammonium iodide; sodium hydride; sodium cyanoborohydride; hydrazine hydrate; trifluoroacetic acid; In methanol; ethanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1016/j.carres.2004.08.016