Technology Process of 4'-O-demethylanhydroepipodophyllol
There total 4 articles about 4'-O-demethylanhydroepipodophyllol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
tetrabutyl ammonium fluoride;
In
tetrahydrofuran;
Ambient temperature;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 98 percent / imidazole / dimethylformamide / 20 h
2: 73 percent / lithium aluminum hydride / tetrahydrofuran / 3 h / Ambient temperature
3: 92 percent / triphenylphosphine, diethyl azodicarboxylate / CH2Cl2 / 3 h
4: tetra-n-butylammonium fluoride / tetrahydrofuran / Ambient temperature
With
1H-imidazole; lithium aluminium tetrahydride; tetrabutyl ammonium fluoride; triphenylphosphine; diethylazodicarboxylate;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 73 percent / lithium aluminum hydride / tetrahydrofuran / 3 h / Ambient temperature
2: 92 percent / triphenylphosphine, diethyl azodicarboxylate / CH2Cl2 / 3 h
3: tetra-n-butylammonium fluoride / tetrahydrofuran / Ambient temperature
With
lithium aluminium tetrahydride; tetrabutyl ammonium fluoride; triphenylphosphine; diethylazodicarboxylate;
In
tetrahydrofuran; dichloromethane;
