153230-70-7

Basic information

• Product Name: 4,4'-bis-O-(dimethyl-tert-butylsilyl)-4'-O-demethylepipodophyllotoxin
• Synonyms: 4,4'-bis-O-(dimethyl-tert-butylsilyl)-4'-O-demethylepipodophyllotoxin
• CAS NO: 153230-70-7
• Molecular Weight: 628.91
• Mol File: 153230-70-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4,4'-bis-O-(dimethyl-tert-butylsilyl)-4'-O-demethylepipodophyllotoxin(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4'-bis-O-(dimethyl-tert-butylsilyl)-4'-O-demethylepipodophyllotoxin(153230-70-7)
• EPA Substance Registry System: 4,4'-bis-O-(dimethyl-tert-butylsilyl)-4'-O-demethylepipodophyllotoxin(153230-70-7)

Safety Data

• Hazardous Substances Data: 153230-70-7(Hazardous Substances Data)

Upstream product

• 6559-91-7 4'-demethylepipodophyllotoxin 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 1372118-32-5 4-O-(dimethyl-tert-butylsilyl)-4'-O-demethylepipodophyllotoxin 
• 1026978-02-8 (5R,5aR,6R,8aR,9S)-9-(tert-Butyl-dimethyl-silanyloxy)-5-[4-(tert-butyl-dimethyl-silanyloxy)-3,5-dimethoxy-phenyl]-6-methoxy-5,5a,6,8,8a,9-hexahydro-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxole 
• 1027383-25-0 Carbonic acid benzyl ester 4-((5R,5aR,6R,8aR,9S)-9-chloro-6-methoxy-5,5a,6,8,8a,9-hexahydro-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl)-2,6-dimethoxy-phenyl ester 
• 153230-73-0 4'-O-carbobenzoxy-4'-O-demethylepipodophyllotoxin 13-methyl ether 
• 153230-78-5 4,4'-bis(tert-butyldimethylsilyl)-4'-O-demethylanhydroepipodophyllol 
• 153230-80-9 4β-(4''-fluoroanilino)-4'-O-demethylanhydroepipodophyllol 
• 153230-72-9 4'-O-demethylepipodophyllotoxin β-methyl ether 
• 153230-79-6 4'-O-demethylanhydroepipodophyllol 
• 1027511-04-1 4-((5R,5aR,8aR,9S)-9-Chloro-5,5a,6,8,8a,9-hexahydro-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl)-2,6-dimethoxy-phenol 
• 683805-50-7 2,2-dimethyl-propionic acid 5-(tert-butyl-dimethyl-silanyloxy)-7-cyanomethyl-8-(4-hydroxy-3,5-dimethoxy-phenyl)-5,6,7,8-tetrahydro-naphtho[2,3-d][1,3]dioxol-6-ylmethyl ester 
• 642409-77-6 2,2-dimethyl-propionic acid 5-(tert-butyl-dimethyl-silanyloxy)-8-[4-(tert-butyl-dimethyl-silanyloxy)-3,5-dimethoxy-phenyl]-7-hydroxymethyl-5,6,7,8-tetrahydro-naphtho[2,3-d][1,3]dioxol-6-ylmethyl ester 
• 642409-78-7 2,2-dimethyl-propionic acid 8-(tert-butyl-dimethyl-silanyloxy)-5-[4-(tert-butyl-dimethyl-silanyloxy)-3,5-dimethoxy-phenyl]-7-hydroxymethyl-5,6,7,8-tetrahydro-naphtho[2,3-d][1,3]dioxol-6-ylmethyl ester 
• 153230-71-8 4,4'-bis(tert-butyldimethylsilyl)-4'-O-demethylepipodophyllotoxin 13-alcohol 

Relevant articles and documents

Synthesis and antiproliferative activity of retroetoposide

Retro-4′-demethyl-4-epipodophyllotoxin 6 was synthesized in eight steps and 10% overall yield from 4′-demethyl-4-epipodophyllotoxin 12. Subsequent coupling of 22 with 1-O-trimethylsilyl-4,6-O-ethylidene-β-D- glucoside 26 afforded retroetoposide 5 which is