methyl 2,3-di-O-acetyl-6-phenylthio-6-deoxy-4-O-(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl)-α-D-glucopyranoside

Base Information

• Chemical Name: methyl 2,3-di-O-acetyl-6-phenylthio-6-deoxy-4-O-(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl)-α-D-glucopyranoside
• CAS No.: 291774-80-6
• Molecular Formula: C₃₁H₄₀O₁₆S
• Molecular Weight: 700.715

Synonyms:methyl 2,3-di-O-acetyl-6-phenylthio-6-deoxy-4-O-(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl)-α-D-glucopyranoside

Chemical Property of methyl 2,3-di-O-acetyl-6-phenylthio-6-deoxy-4-O-(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl)-α-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2,3-di-O-acetyl-6-phenylthio-6-deoxy-4-O-(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl)-α-D-glucopyranoside

There total 2 articles about methyl 2,3-di-O-acetyl-6-phenylthio-6-deoxy-4-O-(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl)-α-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl trichloroimidate (121238-27-5) + methyl 2,3-di-O-acetyl-6-phenylthio-6-deoxy-α-D-glucopyranoside (291774-70-4) → methyl 2,3-di-O-acetyl-6-phenylthio-6-deoxy-4-O-(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl)-α-D-glucopyranoside (291774-80-6)

Guidance literature:

With trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at -50 ℃; for 0.5h;

DOI:10.1016/S0040-4020(01)00959-0

Reference yield:

diphenyldisulfane (882-33-7) → methyl 2,3-di-O-acetyl-6-phenylthio-6-deoxy-4-O-(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl)-α-D-glucopyranoside (291774-80-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / tri-n-butylphosphine / pyridine / 24 h / 20 °C

2: 81 percent / trimethylsilyl trifluoromethanesulfonate / CH₂Cl₂ / 0.5 h / -50 °C

With tributylphosphine; trimethylsilyl trifluoromethanesulfonate; In pyridine; dichloromethane;

DOI:10.1016/S0040-4020(01)00959-0

Reference yield:

methyl 2,3-di-O-acetyl-6-phenylthio-6-deoxy-4-O-(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl)-α-D-glucopyranoside (291774-80-6) → Acetic acid (2S,3R,4S,5S,6S)-3-acetoxy-6-(dichloro-phenylsulfanyl-methyl)-2-methoxy-5-((2R,3S,4S,5R,6R)-3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-4-yl ester

Guidance literature:

With pyridine; sulfuryl dichloride; In tetrachloromethane; at 0 ℃;

DOI:10.1021/ol0062143

upstream raw materials:

2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl trichloroimidate

methyl 2,3-di-O-acetyl-6-phenylthio-6-deoxy-α-D-glucopyranoside

diphenyldisulfane

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 291774-80-6 methyl 2,3-di-O-acetyl-6-phenylthio-6-deoxy-4-O-(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl)-α-D-glucopyranoside

Send

Send

Metric Ton KG G Pound L ML

Send

Send