N-cyclohexyl-N-methyl-4-[2-amino-3-(isopropoxycarbonylmethyl)-3,4-dihydroquinazolin-6-yl]oxybutyramide hydrobromide

Base Information

Chemical Name:N-cyclohexyl-N-methyl-4-[2-amino-3-(isopropoxycarbonylmethyl)-3,4-dihydroquinazolin-6-yl]oxybutyramide hydrobromide
CAS No.:114703-84-3
Molecular Formula:BrH*C₂₄H₃₆N₄O₄
Molecular Weight:525.486
Hs Code.:

Synonyms:N-cyclohexyl-N-methyl-4-[2-amino-3-(isopropoxycarbonylmethyl)-3,4-dihydroquinazolin-6-yl]oxybutyramide hydrobromide

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Chemical Property of N-cyclohexyl-N-methyl-4-[2-amino-3-(isopropoxycarbonylmethyl)-3,4-dihydroquinazolin-6-yl]oxybutyramide hydrobromide

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Technology Process of N-cyclohexyl-N-methyl-4-[2-amino-3-(isopropoxycarbonylmethyl)-3,4-dihydroquinazolin-6-yl]oxybutyramide hydrobromide

There total 4 articles about N-cyclohexyl-N-methyl-4-[2-amino-3-(isopropoxycarbonylmethyl)-3,4-dihydroquinazolin-6-yl]oxybutyramide hydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 105-48-6
isopropyl chloroacetate

: 114703-84-3
N-cyclohexyl-N-methyl-4-[2-amino-3-(isopropoxycarbonylmethyl)-3,4-dihydroquinazolin-6-yl]oxybutyramide hydrobromide

Guidance literature:: Multi-step reaction with 3 steps

1: NaN₃ / dimethylformamide / Ambient temperature

2: 1.) hydrogen, 2.) HCl / Pd-C / ethanol / 3 h / 45 °C

With hydrogenchloride; sodium azide; hydrogen; palladium on activated charcoal; In ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jm00119a015

Reference yield:

: Azido-acetic acid isopropyl ester

: 114703-84-3
N-cyclohexyl-N-methyl-4-[2-amino-3-(isopropoxycarbonylmethyl)-3,4-dihydroquinazolin-6-yl]oxybutyramide hydrobromide

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) hydrogen, 2.) HCl / Pd-C / ethanol / 3 h / 45 °C

With hydrogenchloride; hydrogen; palladium on activated charcoal; In ethanol;
DOI:10.1021/jm00119a015