2-Methylmercaptoiminocarbonyl-6-benzoylaminonaphthalen-hydroiodid

Base Information

• Chemical Name: 2-Methylmercaptoiminocarbonyl-6-benzoylaminonaphthalen-hydroiodid
• CAS No.: 71590-43-7
• Molecular Formula: C₁₉H₁₆N₂OS*HI
• Molecular Weight: 448.327
• Mol file: 71590-43-7.mol

Synonyms:2-Methylmercaptoiminocarbonyl-6-benzoylaminonaphthalen-hydroiodid

Chemical Property of 2-Methylmercaptoiminocarbonyl-6-benzoylaminonaphthalen-hydroiodid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Methylmercaptoiminocarbonyl-6-benzoylaminonaphthalen-hydroiodid

There total 12 articles about 2-Methylmercaptoiminocarbonyl-6-benzoylaminonaphthalen-hydroiodid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-cyano-naphthalene-2-carboxylic acid (5159-60-4) → 2-Methylmercaptoiminocarbonyl-6-benzoylaminonaphthalen-hydroiodid (71590-43-7)

Guidance literature:

Multi-step reaction with 6 steps

1: 99 percent / (COCl)2 / toluene / 22 h / 70 °C

2: 90 percent / NaN₃ / acetone / 1.5 h / 20 °C

3: 67 percent / H₂SO₄ / 1 h / 0 - 20 °C

4: 34 percent / aq. K₂CO₃ / dioxane / 0.17 h / 20 °C

5: pyridine; Et₃N; H₂S / 20 °C

6: acetone / 3 h / 20 °C

With pyridine; sodium azide; oxalyl dichloride; sulfuric acid; hydrogen sulfide; potassium carbonate; triethylamine; In 1,4-dioxane; acetone; toluene;

DOI:10.1021/jm0300072

Reference yield:

6-Cyano-naphthalene-2-carbonyl chloride (68635-22-3) → 2-Methylmercaptoiminocarbonyl-6-benzoylaminonaphthalen-hydroiodid (71590-43-7)

Guidance literature:

Multi-step reaction with 5 steps

1: 90 percent / NaN₃ / acetone / 1.5 h / 20 °C

2: 67 percent / H₂SO₄ / 1 h / 0 - 20 °C

3: 34 percent / aq. K₂CO₃ / dioxane / 0.17 h / 20 °C

4: pyridine; Et₃N; H₂S / 20 °C

5: acetone / 3 h / 20 °C

With pyridine; sodium azide; sulfuric acid; hydrogen sulfide; potassium carbonate; triethylamine; In 1,4-dioxane; acetone;

DOI:10.1021/jm0300072

Reference yield:

naphthalene-2,6-dicarboxylic acid monomethyl ester (7568-08-3) → 2-Methylmercaptoiminocarbonyl-6-benzoylaminonaphthalen-hydroiodid (71590-43-7)

Guidance literature:

Multi-step reaction with 10 steps

1: SOCl₂; DMAP / toluene / 1 h / Heating

2: 13.3 g / NH₃(g) / CH₂Cl₂ / 20 °C

3: 94 percent / pyridine; TFAA / dioxane / 3 h / 20 °C

4: 99 percent / aq. LiOH / tetrahydrofuran / 1.5 h / 20 °C

5: 99 percent / (COCl)2 / toluene / 22 h / 70 °C

6: 90 percent / NaN₃ / acetone / 1.5 h / 20 °C

7: 67 percent / H₂SO₄ / 1 h / 0 - 20 °C

8: 34 percent / aq. K₂CO₃ / dioxane / 0.17 h / 20 °C

9: pyridine; Et₃N; H₂S / 20 °C

10: acetone / 3 h / 20 °C

With pyridine; dmap; lithium hydroxide; thionyl chloride; sodium azide; oxalyl dichloride; sulfuric acid; hydrogen sulfide; ammonia; potassium carbonate; triethylamine; trifluoroacetic anhydride; In tetrahydrofuran; 1,4-dioxane; dichloromethane; acetone; toluene;

DOI:10.1021/jm0300072

upstream raw materials:

2-Thiocarboxamido-6-benzoylaminonaphthalen

methyl iodide

6-cyano-naphthalene-2-carboxylic acid

6-Cyano-naphthalene-2-carbonyl chloride