TM-trans-carveol

Base Information

• Chemical Name: TM-trans-carveol
• CAS No.: 81517-75-1
• Molecular Formula: C₁₄H₂₄O
• Molecular Weight: 208.344
• Mol file: 81517-75-1.mol

Synonyms:TM-trans-carveol

Chemical Property of TM-trans-carveol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of TM-trans-carveol

There total 2 articles about TM-trans-carveol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

trans-1,3,3,5,5-Pentamethyl-4-(1-methylethenyl)-7-oxabicyclo<4.1.0>heptan (78310-15-3) → TM-trans-carveol (81517-75-1)

Guidance literature:

With lithium 2-aminoethylamide; at 110 ℃; for 5h;

DOI:10.1016/S0040-4039(01)92413-X DOI:10.1021/jo00146a024

Reference yield:

tetramethyl-limonene (3,3,5,5-tetramethyl-p-mentha-1,8-diene) (68930-33-6) → TM-trans-carveol (81517-75-1)

Guidance literature:

Multi-step reaction with 2 steps

1: NaHCO₃, m-CPBA / CH₂Cl₂ / 3 h / Ambient temperature

2: 90 percent / N-lithioethylenediamine / 5 h / 110 °C

With lithium 2-aminoethylamide; sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane;

DOI:10.1021/jo00146a024

Reference yield: 85.0%

TM-trans-carveol (81517-75-1) → 5-isopropenyl-2,4,4,6,6-pentamethyl-2-cyclohexenone (81517-77-3)

Guidance literature:

With pyridinium chlorochromate; In dichloromethane; for 2h; Ambient temperature;

DOI:10.1021/jo00146a024

upstream raw materials:

trans-1,3,3,5,5-Pentamethyl-4-(1-methylethenyl)-7-oxabicyclo<4.1.0>heptan

tetramethyl-limonene (3,3,5,5-tetramethyl-p-mentha-1,8-diene)

Downstream raw materials:

5-isopropenyl-2,4,4,6,6-pentamethyl-2-cyclohexenone

TM-cis-carveol