[2-(2-allylphenyl)-1-methylethenyloxy]-t-butyldimethylsilane

Base Information

• Chemical Name: [2-(2-allylphenyl)-1-methylethenyloxy]-t-butyldimethylsilane
• CAS No.: 686767-73-7
• Molecular Formula: C₁₈H₂₈OSi
• Molecular Weight: 288.505
• Mol file: 686767-73-7.mol

Synonyms:[2-(2-allylphenyl)-1-methylethenyloxy]-t-butyldimethylsilane

Chemical Property of [2-(2-allylphenyl)-1-methylethenyloxy]-t-butyldimethylsilane

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of [2-(2-allylphenyl)-1-methylethenyloxy]-t-butyldimethylsilane

There total 2 articles about [2-(2-allylphenyl)-1-methylethenyloxy]-t-butyldimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

tert-butyldimethylsilyl chloride (18162-48-6) + 1-(2-allylphenyl)propan-2-one (686767-79-3) → [2-(2-allylphenyl)-1-methylethenyloxy]-t-butyldimethylsilane (686767-73-7)

Guidance literature:

1-(2-allylphenyl)propan-2-one; With sodium hydride; In tetrahydrofuran; at 0 - 20 ℃;

tert-butyldimethylsilyl chloride; In tetrahydrofuran; for 2h; Further stages.;

DOI:10.1016/j.tet.2003.08.075

Reference yield:

2-(2-bromobenzyl)-2-methyl-1,3-dioxane (686767-78-2) → [2-(2-allylphenyl)-1-methylethenyloxy]-t-butyldimethylsilane (686767-73-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: nBuLi / tetrahydrofuran / -78 - 20 °C

1.2: 22 percent / aq. HCl / methanol / 2 h

2.1: NaH / tetrahydrofuran / 0 - 20 °C

2.2: 95 percent / tetrahydrofuran / 2 h

With n-butyllithium; sodium hydride; In tetrahydrofuran;

DOI:10.1016/j.tet.2003.08.075

upstream raw materials:

tert-butyldimethylsilyl chloride

1-(2-allylphenyl)propan-2-one

2-(2-bromobenzyl)-2-methyl-1,3-dioxane