4-[2-[4-(4-Methoxyphenyl)-1-piperazinyl]ethoxy]-1,2-benzenediamine

Base Information

Chemical Name:4-[2-[4-(4-Methoxyphenyl)-1-piperazinyl]ethoxy]-1,2-benzenediamine
CAS No.:1026089-10-0
Molecular Formula:C₁₉H₂₆N₄O₂
Molecular Weight:342.441
Hs Code.:
DSSTox Substance ID:DTXSID901164549

Synonyms:DTXSID901164549;4-[2-[4-(4-Methoxyphenyl)-1-piperazinyl]ethoxy]-1,2-benzenediamine;1026089-10-0

Suppliers and Price of 4-[2-[4-(4-Methoxyphenyl)-1-piperazinyl]ethoxy]-1,2-benzenediamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-[2-[4-(4-Methoxyphenyl)-1-piperazinyl]ethoxy]-1,2-benzenediamine

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:342.20557608
Heavy Atom Count:25
Complexity:382

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=C(C=C1)N2CCN(CC2)CCOC3=CC(=C(C=C3)N)N

Technology Process of 4-[2-[4-(4-Methoxyphenyl)-1-piperazinyl]ethoxy]-1,2-benzenediamine

There total 7 articles about 4-[2-[4-(4-Methoxyphenyl)-1-piperazinyl]ethoxy]-1,2-benzenediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 856400-21-0
2-nitro-4-{2-[4-(4-methoxyphenyl)piperazin-1-yl]ethoxy}aniline

: 1026089-10-0
4-[2-(4-(4-methoxyphenyl)piperazin-1-yl)-ethoxy]-benzene-1,2-diamine

Guidance literature:: With Ra-Ni; hydrazine hydrate; In ethanol; 1,2-dichloro-ethane; at 50 ℃; for 1h;
DOI:10.1016/j.ejmech.2004.10.006

Reference yield:

: 681259-29-0
4-(2-chloroethoxy)-2-nitroaniline

: 1026089-10-0
4-[2-(4-(4-methoxyphenyl)piperazin-1-yl)-ethoxy]-benzene-1,2-diamine

Guidance literature:: Multi-step reaction with 2 steps

1: 65 percent / K₂CO₃; KI / dimethylformamide / 24 h / 80 °C

2: Ra-Ni; hydrazine hydrate / ethanol; 1,2-dichloro-ethane / 1 h / 50 °C

With Ra-Ni; potassium carbonate; hydrazine hydrate; potassium iodide; In ethanol; 1,2-dichloro-ethane; N,N-dimethyl-formamide;
DOI:10.1016/j.ejmech.2004.10.006

Reference yield:

: 672961-06-7
N-[4-(2-chloroethoxy)-2-nitrophenyl]acetamide

: 1026089-10-0
4-[2-(4-(4-methoxyphenyl)piperazin-1-yl)-ethoxy]-benzene-1,2-diamine

Guidance literature:: Multi-step reaction with 3 steps

1: 75 percent / aq. HCl / 4 h / Heating

2: 65 percent / K₂CO₃; KI / dimethylformamide / 24 h / 80 °C

3: Ra-Ni; hydrazine hydrate / ethanol; 1,2-dichloro-ethane / 1 h / 50 °C

With hydrogenchloride; Ra-Ni; potassium carbonate; hydrazine hydrate; potassium iodide; In ethanol; 1,2-dichloro-ethane; N,N-dimethyl-formamide;
DOI:10.1016/j.ejmech.2004.10.006