ap-9-(o-tert-butylphenyl)-9-methylthiofluorene

Base Information

• Chemical Name: ap-9-(o-tert-butylphenyl)-9-methylthiofluorene
• CAS No.: 226384-22-1
• Molecular Formula: C₂₄H₂₄S
• Molecular Weight: 344.521
• Mol file: 226384-22-1.mol

Synonyms:ap-9-(o-tert-butylphenyl)-9-methylthiofluorene

Chemical Property of ap-9-(o-tert-butylphenyl)-9-methylthiofluorene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ap-9-(o-tert-butylphenyl)-9-methylthiofluorene

There total 1 articles about ap-9-(o-tert-butylphenyl)-9-methylthiofluorene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methylthiol (74-93-1) + sp-9-(o-tert-butylphenyl)-9-fluorenol (65213-15-2) → ap-9-(o-tert-butylphenyl)-9-methylthiofluorene (226384-22-1)

Guidance literature:

With hydrogen bromide; at -15 ℃;

DOI:10.1139/v99-088

Reference yield: 47.8%

ap-9-(o-tert-butylphenyl)-9-methylthiofluorene (226384-22-1) → sp-9-(o-tert-butylphenyl)fluorene (62753-75-7,78737-79-8,202755-78-0) + sp-9-(o-tert-butylphenyl)-3-methylthiofluorene

Guidance literature:

With dimethyl sulfoxide; for 0.5h; Heating;

DOI:10.1139/v99-088

Reference yield:

ap-9-(o-tert-butylphenyl)-9-methylthiofluorene (226384-22-1) → ap-9-(o-tert-butylphenyl)-9-methylfluorene

Guidance literature:

Multi-step reaction with 2 steps

1.1: 24.1 percent / DMSO / 0.5 h / Heating

2.1: n-BuLi / tetrahydrofuran / 6 h / 20 °C

2.2: 82 percent / tetrahydrofuran / 0.08 h

With n-butyllithium; dimethyl sulfoxide; In tetrahydrofuran; 1.1: Rearrangement / 2.1: Metallation / 2.2: Methylation;

DOI:10.1139/v99-088

upstream raw materials:

methylthiol

sp-9-(o-tert-butylphenyl)-9-fluorenol

Downstream raw materials:

sp-9-(o-tert-butylphenyl)fluorene