Methanethiol

Base Information

• Chemical Name: Methanethiol
• CAS No.: 74-93-1
• Deprecated CAS: 63933-47-1,505027-72-5,1417534-47-4,505027-72-5
• Molecular Formula: CH4S
• Molecular Weight: 48.1088
• Hs Code.: 2931909090
• European Community (EC) Number: 200-822-1
• ICSC Number: 0299
• NSC Number: 229573
• UN Number: 1064
• UNII: 2X8406WW9I
• DSSTox Substance ID: DTXSID5026382
• Nikkaji Number: J1.432J
• Wikipedia: Methanethiol
• Wikidata: Q409309,Q83038457,Q82982498
• Metabolomics Workbench ID: 38273
• Mol file: 74-93-1.mol

Synonyms:methanethiol;methanethiolate;methylmercaptan;methylmercaptan, lead (2+) salt;methylmercaptan, mercury (2+) salt;methylmercaptan, sodium salt

Chemical Property of Methanethiol

Chemical Property:

• Appearance/Colour: colourless gas with a garlic-like or rotten cabbage-like smell
• Vapor Pressure: 1900mmHg at 25°C
• Melting Point: -123 °C(lit.)
• Boiling Point: 6 °C(lit.)
• Flash Point: < 71 °C
• PSA: 38.80000
• Density: 0.814 g/cm³
• LogP: 0.54600
• XLogP3: 0.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 48.00337130
• Heavy Atom Count: 2
• Complexity: 2
• Transport DOT Label: Poison Gas Flammable Gas

Purity/Quality:

99.9% ^*data from raw suppliers

Safty Information:

• Pictogram(s): F+,T,N
• Hazard Codes: F+,T,N

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Toxic Gases & Vapors -> Other Toxic Gases & Vapors
• Canonical SMILES: CS
• Inhalation Risk: A harmful concentration of this gas in the air will be reached very quickly on loss of containment.
• Effects of Short Term Exposure: The substance is irritating to the eyes and respiratory tract. The substance may cause effects on the central nervous system. This may result in respiratory depression. Exposure at high levels could cause unconsciousness. Exposure at high levels could cause death. The effects may be delayed. Medical observation is indicated.

Technology Process of Methanethiol

There total 575 articles about Methanethiol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methane (34557-54-5,27936-85-2) → methylthiol (74-93-1) + hydrogen (1333-74-0)

Guidance literature:

With hydrogen sulfide;

Reference yield:

thiophene (188290-36-0,8014-23-1,25233-34-5) + Dimethyldisulphide (624-92-0) → 2-Methylthiophene (554-14-3) + 3,4-dimethylthiophene (632-15-5) + 2,4-dimethylthiophene (638-00-6) + 2,3,4-trimethylthiophene (1795-04-6) + 2,5-DIMETHYLTHIOPHENE (638-02-8) + tetramethylthiophene (14503-51-6) + 3-Methylthiophene (616-44-4,84928-92-7) + methylthiol (74-93-1) + dimethylsulfide (75-18-3) + hydrogen sulfide (7783-06-4)

Guidance literature:

With Co/HZSM-5; at 300 ℃; under 760.051 Torr; Inert atmosphere; Flow reactor;

DOI:10.1134/S1070428018120096

Reference yield:

ametryn (834-12-8) → methylthiol (74-93-1) + N2-ethyl-N4-isopropyl-1,3,5-triazin-2,4-diamine (4150-65-6) + Hydroxyatrazine (2163-68-0)

Guidance literature:

In water; at 24.85 ℃; pH=6; Kinetics; Irradiation;

DOI:10.1002/poc.624

upstream raw materials:

4-methylsulfanyl-3,4-dihydro-2H-pyrrole

methanol

carbon disulfide

2,4,6-tris(methylthio)-1,3,5-triazine

Downstream raw materials:

2-methylmercapto-ethanol

Z-Ala-SMe

2-(2-methylthio)tetrahydropyran

2-[bis(methylthio)methyl]furan

Refernces

• 1、 Wang, Weiming,Li, Yang,Zhang, Xiang,Fang, Weiping,Yang, Yiquan. "Catalytic synthesis of methanethiol from methanol and carbon disulfide over KW/Al2O3 catalysts". . p. 104 - 108. Retrieved 2015.
• 2、 Gutmann, Bernhard,Elsner, Petteri,O'Kearney-Mcmullan, Anne,Goundry, William,Roberge, Dominique M.,Kappe, C. Oliver. "Development of a Continuous Flow Sulfoxide Imidation Protocol Using Azide Sources under Superacidic Conditions". . p. 1062 - 1067. Retrieved 2015.
• 3、 Biswas, Supriya,Ali, Mahammad,Rappoport, Zvi,Salim, Hatim. "Reactions of α-isobutyl-α-(methylthio)methylene Meldrum's acid with primary amines in aqueous DMSO". . p. 1678 - 1685. Retrieved 2006.
• 4、 Nencki. "". . p. 862. Retrieved 1889.
• 5、 Mashkina,Khairulina. "Activity of zeolites in dimethyl sulfide synthesis". . p. 579 - 583. Retrieved 2010.
• 6、 Cao, Jianxin,Kawi, Sibudjing,Liu, Fei,Pei, Lijie,Wang, Xiaodan,Yang, Anjie,Yao, Mengqin,Zhao, Tianxiang. "Thiolation behaviors of methanol catalyzed by bifunctional ZSM-5@t-ZrO2 catalyst". . . Retrieved 2021/08/26.
• 7、 -. "PROCESS FOR THE PREPARATION OF METHYL MERCAPTAN". Paragraph 0058-0060. . Retrieved 2020/11/30.