benzyl (3S,4S)-3,4-trans-3-[(tert-butoxycarbonyl)amino]-4-hydroxypiperidine-1-carboxylate

Base Information

Chemical Name:benzyl (3S,4S)-3,4-trans-3-[(tert-butoxycarbonyl)amino]-4-hydroxypiperidine-1-carboxylate
CAS No.:1052715-77-1
Molecular Formula:C₁₈H₂₆N₂O₅
Molecular Weight:350.415
Hs Code.:

Synonyms:benzyl (3S,4S)-3,4-trans-3-[(tert-butoxycarbonyl)amino]-4-hydroxypiperidine-1-carboxylate

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Chemical Property of benzyl (3S,4S)-3,4-trans-3-[(tert-butoxycarbonyl)amino]-4-hydroxypiperidine-1-carboxylate

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Technology Process of benzyl (3S,4S)-3,4-trans-3-[(tert-butoxycarbonyl)amino]-4-hydroxypiperidine-1-carboxylate

There total 11 articles about benzyl (3S,4S)-3,4-trans-3-[(tert-butoxycarbonyl)amino]-4-hydroxypiperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 14.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 1624258-63-4
(1S,6R)-7-oxa-3-aza-bicyclo[4.1.0]heptane-3-carboxylic acid benzyl ester

: 1052715-77-1,859854-67-4,1549812-60-3
benzyl (3S,4S)-3,4-trans-3-[(tert-butoxycarbonyl)amino]-4-hydroxypiperidine-1-carboxylate

: 724787-54-6
(3S,4S)-4-tert-butoxycarbonylamino-3-hydroxypiperidine-1-carboxylic acid benzyl ester

Guidance literature:: (1S,6R)-7-oxa-3-aza-bicyclo[4.1.0]heptane-3-carboxylic acid benzyl ester; With ammonium hydroxide; In ethanol; water; at 20 ℃; for 48h;

di-tert-butyl dicarbonate; In dichloromethane; at 20 ℃;

Reference yield: 13.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 1624258-63-4
(1S,6R)-7-oxa-3-aza-bicyclo[4.1.0]heptane-3-carboxylic acid benzyl ester

: 1052715-77-1,859854-67-4,1549812-60-3
benzyl (3S,4S)-3,4-trans-3-[(tert-butoxycarbonyl)amino]-4-hydroxypiperidine-1-carboxylate

Guidance literature:: (1S,6R)-7-oxa-3-aza-bicyclo[4.1.0]heptane-3-carboxylic acid benzyl ester; With ammonium hydroxide; In ethanol; water; at 20 ℃; for 48h;

di-tert-butyl dicarbonate; In dichloromethane; at 20 ℃; for 4h;